Results 161 to 170 of about 2,687,827 (299)

The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism

Nature Reviews. Cancer, 2019
G. Hoxhaj, B. Manning
semanticscholar   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Anti-inflammatory activity of α-tomatine <i>via</i> inhibition of the MAPK and NF-κB signaling pathway <i>in vitro</i> and <i>ex vivo</i>. [PDF]

Int J Med Sci
Chen CW, Hsieh CC, Hsieh YT, Lin MJ, Chiu PH, Juan CC, Lieu FK, Wang SW, Wang PS.   +8 more
europepmc   +1 more source

Cytokines in ovarian folliculogenesis, oocyte maturation and luteinisation

Molecular Reproduction and Development, 2014
Sarah L. Field, T. Dasgupta, M. Cummings, N. Orsi   +3 more
semanticscholar   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Emerging roles of astrocytes in autonomic control of blood pressure and hypertension. [PDF]

Am J Physiol Cell Physiol
Verma H, Feng Earley Y.
europepmc   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source

The Role of Salivary Diagnostics in Early Detection of Systemic and Oral Diseases: A Comprehensive Review. [PDF]

Cureus
Shah SD, Gupta S, Pamu PK, Shukla JP, Nayak S, Chatterjee K.   +5 more
europepmc   +1 more source

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

Nature, 2015
J. V. Moltke, M. Ji, Hong-Erh Liang, R. Locksley   +3 more
semanticscholar   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source