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Distinct Rb expression pattern in HPV‐associated neuroendocrine carcinomas of the uterine cervix
Most uterine cervical neuroendocrine carcinoma (UCNEC) cases are HPV‐associated and are characterized by partial loss of Rb, p16 overexpression, and cyclin D1 negativity. A minority of UCNECs exhibit a distinct pattern, characterized by HPV negativity, retained Rb expression, focal p16 expression and cyclin D1 positivity.
Nobuko Yasutake +12 more
wiley +1 more source
Pigmented spindle cell nevus of Reed (PSCN) is a subtype of Spitz nevus mainly characterized by MYO5A::NTRK3 fusion. Our optimized pan‐TRK protocol stained 16/79 (20.3%) PSCNs (diffuse, granular, cytoplasmic staining of moderate intensity) and revealed high values of specificity (94.4%–96.2%) and positive predictive value (92.3%) for the detection of ...
Costantino Ricci +19 more
wiley +1 more source
The Critical Contribution of Pathology Technicians to Veterinary Diagnostics, Research and Teaching. [PDF]
Araújo D, Carvalho F, Vale N, Amorim I.
europepmc +1 more source
Mast cells: The forgotten players in type 2 inflammation - From nasal cytology to chronic rhinosinusitis with nasal polyps and beyond. [PDF]
Gelardi M +3 more
europepmc +1 more source
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Cell Block in Cytological Diagnostics: Review of Preparatory Techniques
<b><i>Objective:</i></b> The cell block (CB) technique refers to the processing of sediments, blood clots, or grossly visible tissue fragments from cytological specimens into paraffin blocks that can be cut and stained by the same
Ivana Kholová, Leena Krogerus
exaly +2 more sources
Use of Enzymes to Improve Cytological Techniques
Science, 1943N W, Stuart, S L, Emsweller
exaly +3 more sources
Overview of Ancillary Techniques in Cervical Cytology
Acta Cytologica, 2023Background: The association between high-risk serotypes of human papillomavirus (hr-HPV) and cervical cancer is well-established. Summary: In order to improve the sensitivity of cervical cytology testing, hr-HPV testing has rapidly become part of routine cervical cancer screening, either in conjunction with cytology or as primary testing.
Andrea D. Olivas +2 more
openaire +2 more sources

