Results 81 to 90 of about 65,506 (309)

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

open access: yesThe Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi   +21 more
wiley   +1 more source

Lung cancer cytology: Can any of the cytological methods replace histopathology?

open access: yesJournal of Cytology, 2020
Background: Diagnosis of lung cancer can be made in two ways: histopathological and cytopathological. Cytological methods in the diagnosis of lung lesions are generally thought to be one of the most successful tactics. Aims: This study aimed at comparing
Magdalena Chrabañska   +3 more
doaj   +1 more source

Morphological and physiological variability of species of Meloidogyne in West Africa and implications of their control [PDF]

open access: yes, 1978
The extreme morphological and physiological variability of certain rootknot nematodes (Meloidogyne spp.) and its implication on the development of control methods of these parasites, based upon crop rotations and the use of resistant varieties of ...
Netscher, C.
core   +1 more source

Two-Stage Convolutional Neural Network for Breast Cancer Histology Image Classification

open access: yes, 2018
This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.
DC Cireşan   +7 more
core   +1 more source

Variation of specific morphological traits and ploidy level of five "aegilops" l. species in Morocco [PDF]

open access: yes, 2003
Variation of specific morphological traits and ploidy level of five Aegilops L. species in Morocco.The genus Aegilops L. represents an important natural source of useful genes for wheat breeding, with particular emphasis on biotic and abiotic stress ...
Assali, Nourredine   +2 more
core   +4 more sources

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong   +5 more
wiley   +1 more source

Trends in Epithelial Cell Abnormalities Observed on Cervical Smears over a 21-Year Period in a Tertiary Care Hospital in Kuwait

open access: yesSultan Qaboos University Medical Journal, 2015
Objectives: This study aimed to analyse trends in epithelial cell abnormalities (ECAs) in cervical cytology at a tertiary care hospital in Kuwait.
Kusum Kapila   +5 more
doaj   +2 more sources

Polyetheretherketone as a Biomaterial for Spinal Applications [PDF]

open access: yes, 2006
Threaded lumbar interbody spinal fusion devices (TIBFD) made from titanium have been reported to be 90% effective for single-level lumbar interbody fusion, although radiographic determination of fusion has been intensely debated in the literature.
Estes, Bradley T.   +5 more
core   +1 more source

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang   +7 more
wiley   +1 more source

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

open access: yesAnimal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun   +6 more
wiley   +1 more source

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