Results 71 to 80 of about 5,512,194 (292)

Computed tomography-guided fine-needle aspiration biopsy

open access: yesSão Paulo Medical Journal
The therapeutic and prognostic evaluation of malignant neoplasias depends largely upon a precise morphologic diagnosis. Several papers have focused on the importance of fine-needle aspiration under computed tomography guidance in the diagnosis of ...
Gilda da Cunha Santos   +4 more
doaj   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

open access: yesAdvanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang   +5 more
wiley   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu   +5 more
wiley   +1 more source

Carcinoembryonic Antigen Messenger RNA in Pelvic Lavage Fluid Predicts Local Recurrence After Curative‐Intent Resection of Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Pelvic lavage carcinoembryonic antigen (CEA) mRNA was quantified in 178 patients undergoing curative‐intent resection for rectal cancer. Positive pelvic lavage CEA mRNA was significantly associated with local recurrence and provided additional prognostic information beyond circumferential resection margin (CRM) status.
Hiroyuki Asai   +9 more
wiley   +1 more source

Lung malignancy: Diagnostic accuracies of bronchoalveolar lavage, bronchial brushing, and fine needle aspiration cytology

open access: yesLung India, 2016
Background: Early diagnosis of lung cancer plays a pivotal role in reducing lung cancer death rate. Cytological techniques are safer, economical and provide quick results.
Rateesh Sareen, C L Pandey
doaj   +1 more source

Comparative analysis of cytomorphologic features of thyroid lesions using various cytological staining techniques [PDF]

open access: yes, 2018
INTRODUCTION: Thyroid lesions are common clinical problem. Fine needle aspiration cytology of thyroid gland is useful minimally invasive preliminary investigation.
Meenakshi, N
core  

A well‐resolved phylogeny of Cuscuta subgenus Monogynella based on data drawn from all three plant genomes

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Cuscuta (dodders) consists of ~200 species circumscribed into four subgenera (Monogynella, Cuscuta, Pachystigma, and Grammica) and is the only parasitic genus in Convolvulaceae (the morning‐glory family). This group shows a significant diversity in plastid functionality and represents a rare mixotrophic system among parasitic plants ...
Asawari Albal, Saša Stefanović
wiley   +1 more source

Specificity and Sensitivity of Cytological Techniques for Rapid Diagnosis of Neoplastic and Non-neoplastic Lesions of Canine Mammary Gland

open access: yesBrazilian Journal of Veterinary Pathology, 2011
The present study aimed at evaluating diagnostic accuracy and efficacy of cytology for rapid diagnosis and differentiation of various mammary affections of canines and the comparison of cytological findings with that of histopathology.
Shivani Sangha   +3 more
doaj   +1 more source

Differential Diagnosis of Mucopolysaccharidoses Types I, II, III, IVA, and VI Through Analysis of Leukocytic Inclusions

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mucopolysaccharidoses (MPS) are lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs), which can lead to cytoplasmic alterations in leukocytes. The objective of this study was to characterize leukocyte inclusions in patients with different types of MPS and assess their diagnostic relevance.
Márcio A. W. Melo   +5 more
wiley   +1 more source

Influência da lubrificação do espéculo vaginal na interpretação da colpocitologia oncótica The effect of vaginal speculum lubrication on cervical cytology findings

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2005
OBJETIVO: avaliar a interferência de dois lubrificantes vaginais (vaselina e silicone) na interpretação da colpocitologia oncótica. MÉTODO: realizou-se estudo transversal, prospectivo, com 100 pacientes, entre agosto e outubro de 2003. As pacientes foram
Josie Bittencourt da Silva   +5 more
doaj   +1 more source

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