Emerging roles of cancer-testis antigenes, semenogelin 1 and 2, in neoplastic cells
Cell Death Discovery, 2021 Cancer-testicular Antigens (CTAs) belong to a group of proteins that under normal conditions are strictly expressed in a male’s reproductive tissues. However, upon malignisation, they are frequently re-expressed in neoplastic tissues of various origin. A
Oleg Shuvalov +5 more
doaj +1 more source
A Single-Arm, Proof-Of-Concept Trial of Lopimune (Lopinavir/Ritonavir) as a Treatment for HPV-Related Pre-Invasive Cervical Disease [PDF]
, 2016 BACKGROUND: Cervical cancer is the most common female malignancy in the developing nations and the third most common cancer in women globally. An effective, inexpensive and self-applied topical treatment would be an ideal solution for treatment of ...
A Kwara +48 more
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Estimating the accuracy of anal cytology in the presence of an imperfect reference standard. [PDF]
PLoS ONE, 2010 The study aim is to estimate sensitivity and specificity of anal cytology for histologic HSIL in analyses adjusted for the imperfect biopsy reference standard.Retrospective cohort study of an anal dysplasia screening program for HIV infected adults.
William C Mathews +5 more
doaj +1 more source
The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase
Cell Death and Disease, 2021 The RING-finger protein Pirh2 is a p53 family-specific E3 ubiquitin ligase. Pirh2 also ubiquitinates several other important cellular factors and is involved in carcinogenesis. However, its functional role in other cellular processes is poorly understood.
Alexandra Daks +9 more
doaj +1 more source
Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]
, 2016 Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
AT Cruz +39 more
core +3 more sources
Is Aporia crataegi unsuitable host of Wolbachia symbionts?
Вестник защиты растений, 2021 The Black-veined White Aporia crataegi L. (Lepidoptera: Pieridae) is a transpalearctic pest species. Its abundance varies in different regions and in some territories populations decreasing and extinction observed.
Роман Андреевич Быков +3 more
doaj +1 more source
Effect of Preanalytical Processing of ThinPrep Specimens on Detection of High-Risk Human Papillomavirus by the Aptima HPV Assay [PDF]
, 2014 Two important preanalytical protocols performed on liquid-based cytological specimens, namely, automated cytology processing and glacial acetic acid (GAA) treatment, may occur prior to the arrival of specimens in a molecular diagnostics laboratory ...
Amrhein, Robert D. +7 more
core +2 more sources
BMC Genomics, 2018 Background Cerebrovascular dysfunction plays a critical role in the pathogenesis of Alzheimer’s disease (AD): the most common cause of dementia in the elderly.
Natalia A. Stefanova +4 more
doaj +1 more source
SEMG1/2 augment energy metabolism of tumor cells
Cell Death and Disease, 2020 SEMG1 and SEMG2 genes belong to the family of cancer-testis antigens (CTAs), whose expression normally is restricted to male germ cells but is often restored in various malignancies.
Oleg Shuvalov +8 more
doaj +1 more source
The Role of E3 Ligase Pirh2 in Disease
Cells, 2022 The p53-dependent ubiquitin ligase Pirh2 regulates a number of proteins involved in different cancer-associated processes. Targeting the p53 family proteins, Chk2, p27Kip1, Twist1 and others, Pirh2 participates in such cellular processes as proliferation,
Alexandra Daks +5 more
doaj +1 more source