Results 1 to 10 of about 64,045 (116)

Emerging roles of cancer-testis antigenes, semenogelin 1 and 2, in neoplastic cells

Cell Death Discovery, 2021
Cancer-testicular Antigens (CTAs) belong to a group of proteins that under normal conditions are strictly expressed in a male’s reproductive tissues. However, upon malignisation, they are frequently re-expressed in neoplastic tissues of various origin. A
Oleg Shuvalov, Alyona Kizenko, Alexey Petukhov, Olga Fedorova, Alexandra Daks, Nikolai Barlev   +5 more
doaj   +1 more source

Mesenchymal stem cells lose the senescent phenotype under 3D cultivation

Stem Cell Research & Therapy, 2023
Background Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of the in vivo microenvironment ...
O. Krasnova, A. Kovaleva, A. Saveleva, K. Kulakova, O. Bystrova, M. Martynova, A. Domnina, J. Sopova, I. Neganova   +8 more
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Evaluation of the α-casein (CSN1S1) locus as a potential target for a site-specific transgene integration

Scientific Reports, 2022
Transgenic animals are an important tool in biotechnology, including the production of recombinant proteins in the milk. Traditionally, expression constructs are based on hybrid vectors bearing mammary gland specific regulatory elements from the α-casein
A. V. Smirnov, G. V. Kontsevaya, T. A. Shnaider, A. M. Yunusova, N. A. Feofanova, L. A. Gerlinskaya, I. A. Serova, O. L. Serov, N. R. Battulin   +8 more
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Alpha-actnin-4 (ACTN4) selectively affects the DNA double-strand breaks repair in non-small lung carcinoma cells

Biology Direct, 2022
Background ACTN4 is an actin-binding protein involved in many cellular processes, including cancer development. High ACTN4 expression is often associated with a poor prognosis.
Daria Kriger, Ksenia Novitskaya, Giomar Vasileva, Ekaterina Lomert, Nikolai D. Aksenov, Nikolai A. Barlev, Dmitri Tentler   +6 more
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Amino acid sequence associated with bacteriophage recombination site helps to reveal genes potentially acquired through horizontal gene transfer

BMC Bioinformatics, 2020
Background Horizontal gene transfer, i.e. the acquisition of genetic material from nonparent organism, is considered an important force driving species evolution. Many cases of horizontal gene transfer from prokaryotes to eukaryotes have been registered,
Maria A. Daugavet, Sergey V. Shabelnikov, Olga I. Podgornaya   +2 more
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Estimating the accuracy of anal cytology in the presence of an imperfect reference standard. [PDF]

PLoS ONE, 2010
The study aim is to estimate sensitivity and specificity of anal cytology for histologic HSIL in analyses adjusted for the imperfect biopsy reference standard.Retrospective cohort study of an anal dysplasia screening program for HIV infected adults.
William C Mathews, Edward R Cachay, Joseph Caperna, Amy Sitapati, Bard Cosman, Ian Abramson   +5 more
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Gas chromatography-mass spectrometry in the taxonomy of Miscanthus

Вавиловский журнал генетики и селекции, 2020
Chemotaxonomy as a system approach deals with intra- and interspecific polymorphism of a group of taxa in order to clarify their taxonomic positions or to select material for selection or introduction.
N. M. Slynko, N. V. Burmakina, O. M. Potseluyev, S. Yu. Kapustyanchik, G. Yu. Galitsin, T. N. Goryachkovskaya, L. V. Kuybida, S. V. Shekhovtsov, S. E. Peltek, V. K. Shumny   +9 more
doaj   +1 more source

Association of cerebrovascular dysfunction with the development of Alzheimer’s disease-like pathology in OXYS rats

BMC Genomics, 2018
Background Cerebrovascular dysfunction plays a critical role in the pathogenesis of Alzheimer’s disease (AD): the most common cause of dementia in the elderly.
Natalia A. Stefanova, Kseniya Yi Maksimova, Ekaterina A. Rudnitskaya, Natalia A. Muraleva, Nataliya G. Kolosova   +4 more
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Genetic variability of spelt factor gene in Triticum and Aegilops species

BMC Plant Biology, 2020
Background Threshability, rachis fragility and spike shape are critical traits for the domestication and evolution of wheat, determining the crop yield and efficiency of the harvest.
Valeriya Vavilova, Irina Konopatskaia, Alexandr Blinov, Elena Ya. Kondratenko, Yuliya V. Kruchinina, Nikolay P. Goncharov   +5 more
doaj   +1 more source

Phosphorus deficiency induces sexual reproduction in the dinoflagellate Prorocentrum cordatum

Scientific Reports, 2023
Nitrogen (N) and phosphorus (P) are essential elements whose availability promotes successful growth of phytoplankton and governs aquatic primary productivity.
Vera Kalinina, Mariia Berdieva, Nikolay Aksenov, Sergei Skarlato   +3 more
doaj   +1 more source