Results 51 to 60 of about 272,810 (306)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2018 Rapid development of high-performance genomic, transcriptomic, proteomic and metabolic technologies led to an information explosion in the field of plant biology and agrobiology.
T. V. Ivanisenko +6 more
doaj +1 more source
Cytology of the prostate [PDF]
Journal of Clinical Pathology, 1964 A series of prostates has been studied cytologically by making smears directly from surgically excised glands. The cytological findings in these smears are described. Benign conditions of the prostate can be readily diagnosed by this means but it is not a satisfactory method for finding latent carcinomas.
openaire +2 more sources
, 2017 Objectives: Epidermal growth factor receptor (EGFR) mutation testing is standard practice after lung adenocarcinoma diagnosis, and provision of high-quality tumor tissue is ideal. However, there are knowledge gaps regarding the utility of cytology or low
楊志新 +1 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Transcriptomic response of marine dinoflagellate Prorocentrum cordatum to phosphorus deficiency
Scientific ReportsPhosphorus is crucial for marine phytoplankton viability as a key biogenic element. Under phosphorus deficiency, dinoflagellates exhibit changes in their feeding regime, alterations in transporters functioning, a reduction in cell proliferation rate and,
Vera Kalinina +4 more
doaj +1 more source
The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase
Cell Death and Disease, 2021 The RING-finger protein Pirh2 is a p53 family-specific E3 ubiquitin ligase. Pirh2 also ubiquitinates several other important cellular factors and is involved in carcinogenesis. However, its functional role in other cellular processes is poorly understood.
Alexandra Daks +9 more
doaj +1 more source
Random chromosome distribution in the first meiosis of F1 disomic substitution line 2R(2D) x rye hybrids (ABDR, 4× = 28) occurs without bipolar spindle assembly [PDF]
Comparative Cytogenetics, 2020 The assembly of the microtubule-based spindle structure in plant meiosis remains poorly understood compared with our knowledge of mitotic spindle formation.
Dina B. Loginova +2 more
doaj +3 more sources
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han +4 more
wiley +1 more source