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Presentation of an Immunodominant Immediate-Early CD8+ T Cell Epitope Resists Human Cytomegalovirus Immunoevasion. [PDF]
Control of human cytomegalovirus (HCMV) depends on CD8+ T cell responses that are shaped by an individual's repertoire of MHC molecules. MHC class I presentation is modulated by a set of HCMV-encoded proteins.
Ameres, Stefanie+6 more
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ABSTRACTCytomegalovirus (CMV), the largest of the herpesviruses, causes a wide range of clinical syndromes, from asymptomatic infection to severe disease in immunocompromised hosts. Laboratory methods for diagnosis include molecular testing, antigenemia, culture, serology, and histopathology.
M Veronica, Dioverti+1 more
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Cytomegalovirus (CMV) is the most common cause of congenital infections in developed countries because is capable of infecting the fetus after both primary and recurrent maternal infection, and because the virus may be spread for years through infected ...
Giovanni Nigro+2 more
doaj +1 more source
Cytomegalovirus infection is one of the critical and life-threatening infectious complications in patients after allogeneic hematopoietic stem cell transplantation.
A. A. Dmitrova+3 more
doaj +1 more source
To date, no herpesvirus has been shown to latently persist in fibroblastic cells. Here, we show that murine cytomegalovirus, a β-herpesvirus, persists for the long term and across organs in PDGFRα-positive fibroblastic cells, with similar or higher ...
Katarzyna M. Sitnik+8 more
doaj +1 more source
Genotype distribution, viral load and clinical characteristics of infants with postnatal or congenital cytomegalovirus infection. [PDF]
BACKGROUND:Congenital cytomegalovirus infection is a leading cause of long-term sequelae. Cytomegalovirus is also frequently transmitted to preterm infants postnatally, but these infections are mostly asymptomatic.
Joppe Nijman+6 more
doaj +1 more source
Cytomegaloviral hepatitis in children: current state of the problem
Cytomegalovirus infection is an infectious disease caused by the highly common herpes virus type 5, characterized by polytropic lesions of organs and systems, complex immunological reactions on the part of the macroorganism, with the formation of a long,
G. S. Karpovich+3 more
doaj +1 more source
Cytomegalovirus congenital infection – cause of neurosensorial hearing loss [PDF]
Cytomegalovirus infection is a major public health problem, because annually there are born increasingly more children with this infection. Numerous studies have shown that cytomegalovirus infection is an important cause of hearing loss.
Dana-Teodora Anton-Păduraru+4 more
doaj +1 more source
Background To report the first case of belatacept-associated multidrug-resistant Cytomegalovirus retinitis in a kidney transplant recipient. Case presentation A 76-year-old African male renal allograft recipient was admitted for acute visual loss of the ...
Pierre-Guillaume Deliège+5 more
doaj +1 more source
Cytomegalovirus infection is one of the most serious pathogens affecting solid organ transplant recipients. Cytomegalovirus has been identified as a risk factor for graft rejection, cardiac allograft vasculopathy and is associated with increased ...
Sandra Jaksic Jurinjak+2 more
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