Results 31 to 40 of about 190,009 (311)

Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients

Infectious Diseases of Poverty, 2020
Background Accurately differentiating pneumocystis from cytomegalovirus pneumonia is crucial for correct therapy selection in AIDS patients. Hence, the goal of this study was to compare the computerized tomography (CT) features of pneumocystis pneumonia ...
Chun-Jing Du, Jing-Yuan Liu, Hui Chen, Shuo Yan, Lin Pu, Hao-Feng Xiong, Pan Xiang, Chuan-Sheng Li, Ming Zhang, Ru-Ming Xie, Bu-Dong Chen, Ang Li   +11 more
doaj   +1 more source

Sequential anti-cytomegalovirus response monitoring may allow prediction of cytomegalovirus reactivation after allogeneic stem cell transplantation

, 2012
Background: Reconstitution of cytomegalovirus-specific CD3+CD8+ T cells (CMV-CTLs) after allogeneic hematopoietic stem cell transplantation (HSCT) is necessary to bring cytomegalovirus (CMV) reactivation under control. However, the parameters determining
Matthias Eder (21135), Borchers, Sylvia, Benno Wölk, Sylvia Borchers, Arnold Ganser, Pabst, Brigitte, Mischak-Weissinger, Eva Maria, Michael Stadler, Elke Dammann, Andrea Jarisch, Lehrnbecher, Thomas, Arnold Ganser (4454), Eva M. Weissinger (111202), Meral Yildiz, Schneider, Gisbert, Matthias Eder, Peter Bader, Melanie Bremm (111153), Koehl, Ulrike, Thomas Klingebiel, Michael Stadler (111171), Ulrike Koehl, Hans Martin, Benno Wölk (111163), Stadler, Michael, Thomas Lehrnbecher, Sylvia Borchers (111150), Wölk, Benno, Hans Martin (111179), Meral Yildiz (111168), Dammann, Elke, Thomas Klingebiel (111191), Brigitte Pabst (111160), Bader, Peter, Eder, Matthias, Jarisch, Andrea, Brigitte Pabst, Gisbert Schneider, Elke Dammann (111158), Gisbert Schneider (17096), Ulrike Koehl (111209), Thomas Lehrnbecher (111156), Klingebiel, Thomas, Esser, Ruth, Eva M. Weissinger, Ruth Esser (111165), Ganser, Arnold, Yildiz, Meral, Melanie Bremm, Peter Bader (111174), Eva M Weissinger, Bremm, Melanie, Andrea Jarisch (111185), Ruth Esser, Weissinger, Eva M., Köhl, Ulrike, Martin, Hans   +56 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infection [PDF]

, 1987
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that in vivo application of recombinant human IL-2 (rhIL-2) can enhance the antiviral effect of a limited number of CD8+T lymphocytes, not only in ...
Reddehase, Matthias J., W Mutter, Koszinowski, Ulrich H., Wolfgang Mutter, J. Reddehase, M J Reddehase, U H Koszinowski, Koszinowski, Ulrich, Mutter, Wolfgang, Ulrich H. Koszinowski   +9 more
core   +1 more source

Independent predictors of cytomegalovirus vertical transmission in children with perinatal HIV contact

Журнал инфектологии, 2014
102 pair «HIV infected pregnant women with cytomegalovirus infection – HIV negative child» were examined. Cytomegalovirus vertical transmission were realized in 20% women.
V. B. Denisenko, E. N. Simovanian, V. V. Pushkarnaya   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Antibodies Are Not Essential for the Resolution of Primary Cytomegalovirus Infection but Limit Dissemination of Recurrent Virus [PDF]

, 1994
Virus shedding from the epithelial cells of the serous acini of salivary glands is a major source for the horizontal transmission of cytomegalovirus. These cells are, different to other tissues, exempt from CD8 T lymphocyte control. CD4 T lymphocytes are
Crnkovic, Irena, Koszinowski, Ulrich H., Koszinovski, UH, I Crnković, U H Koszinowski, Pavic, Ivica, S Jonjić, Lucin, Pero, I Pavić, B Polić, P Lucin, Polic, Bojan, Jonjic, Stipan   +12 more
core   +1 more source

ASSOCIATION OF SEROPOSITIVITY FOR CMV IGM AND IGG WITH ADVERSE PREGNANCY OUTCOME

Pakistan Armed Forces Medical Journal, 2021
Objective: To find out the prevalence of antibodies against cytomegalovirus and their association with adverse pregnancy outcome in women, at Isra University Hospital Hyderabad. Study Design: Cross-sectional study.
Ambreen Amna, Farkhunda Nadeem, Amin Fahim, Altaf Hussian Jatoi, Kanwal Abbas, Sumayya Anas   +5 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Structure and expression of murine cytomegalovirus immediate-early gene 2 [PDF]

, 1991
The immediate-early gene ie2 of murine cytomegalovirus was characterized. The 1.75-kb ie2 transcript is spliced from three exons, of 78, 124, and 1,283 nucleotides, which are separated by introns of 1,245 and 364 nucleotides.
Koszinowski, Ulrich H., Messerle, Martin, Keil, Günther M.   +2 more
core