Cytolytic T lymphocyte recognition of the murine cytomegalovirus nonstructural immediate-early protein pp89 expressed by recombinant vaccinia virus [PDF]
The murine immediate-early (IE) protein pp89 is a nonstructural virus- encoded phosphoprotein residing in the nucleus of infected cells, where it acts as transcriptional activator.
Bertholet, Christine +4 more
core +4 more sources
The authors studied 58 infants hospitalized for pneumonia in a semi-intensive care unit. Age ranged from 1 complete to 6 incomplete months. The infants were sent from another hospital in 20 cases and from home in a further 38.
Bernardo Ejzenberg +5 more
doaj +1 more source
Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]
The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Koszinowski, Ulrich H. +4 more
core +1 more source
Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes [PDF]
Although the relative contribution of different immune effector functions to clearing tissues of cytomegalovirus is controversial, the contribution of CD8+ T lymphocytes has generally been accepted as essential. In this report, we show that under certain
Jonjic, Stipan +4 more
core
Leucoreduction of blood components. an effective way to increase blood safety? [PDF]
Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria +6 more
core +1 more source
Cytomegalovirus Treatment [PDF]
In treating cytomegalovirus (CMV) infection, it is crucial to decide whether one is treating pre-emptively or if one is treating established disease. Disease may be further divided into viral syndrome and tissue-invasive disease. Generally, mild disease in immunosuppressed patients may be treated with oral valganciclovir.
openaire +2 more sources
Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size [PDF]
Cytomegalovirus (CMV) infection is one of the most common persistent viral infections in humans worldwide and is epidemiologically associated with many adverse health consequences during aging.
A Harari +47 more
core +1 more source
Lenticulostriate vasculopathy is associated with various disorders, in particular cytomegalovirus infection, which can cause neurological consequences. We wanted to evaluate the association of lenticulostriate vasculopathy and cytomegalovirus infection ...
Syuan-Yu Hong +3 more
doaj +1 more source
Dynamic Model of Cytomegalovirus with Vertical Infection
In this paper,the problem of vertical infection of babies with cytomegalovirus in breast milk is considered,a dynamic model of cytomegalovirus is established,the equilibrium stability condition of the model is given,and the effect of randomness of breast
LIDongmei, FUYuli, WANGQi
doaj +1 more source
A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]
A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael +5 more
core +1 more source

