Results 51 to 60 of about 202,572 (291)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Characterization of the major immediate-early polypeptides encoded by murine cytomegalovirus [PDF]

, 1985
The immediate-early (IE) infected cell proteins induced by the murine cytomegalovirus (Smith strain) were studied. These polypeptides were identified as IE proteins by their synthesis in the presence of actinomycin D after removal from a protein ...
Fibi, Mathias R., Koszinowski, Ulrich H., Keil, Günther M.   +2 more
core   +1 more source

Independent predictors of cytomegalovirus vertical transmission in children with perinatal HIV contact

Журнал инфектологии, 2014
102 pair «HIV infected pregnant women with cytomegalovirus infection – HIV negative child» were examined. Cytomegalovirus vertical transmission were realized in 20% women.
V. B. Denisenko, E. N. Simovanian, V. V. Pushkarnaya   +2 more
doaj   +1 more source

ASSOCIATION OF SEROPOSITIVITY FOR CMV IGM AND IGG WITH ADVERSE PREGNANCY OUTCOME

Pakistan Armed Forces Medical Journal, 2021
Objective: To find out the prevalence of antibodies against cytomegalovirus and their association with adverse pregnancy outcome in women, at Isra University Hospital Hyderabad. Study Design: Cross-sectional study.
Ambreen Amna, Farkhunda Nadeem, Amin Fahim, Altaf Hussian Jatoi, Kanwal Abbas, Sumayya Anas   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Characterization of the murine cytomegalovirus early transcription unit e1 that is induced by immediate-early proteins [PDF]

, 1990
The regulation of murine cytomegalovirus early (E) gene expression was studied in the cell line B25, which is stably transfected with the immediate-early ie1/ie3 gene complex.
Bühler, Bernhard, Koszinowski, Ulrich H., Keil, Günther M., Weiland, Frank   +3 more
core   +1 more source

Immunosenescence and Cytomegalovirus: where do we stand after a decade? [PDF]

, 2010
Since Looney at al. published their seminal paper a decade ago it has become clear that many of the differences in T cell immunological parameters observed between young and old people are related to the age-associated increasing prevalence of infection ...
Grubeck-Loebenstein, B, Pawelec, Graham, Sven D Koch, Pawelec, G, Maier, Andrea B., Akbar, A, S D Koch (16139375), Beverly, P, Strindhall, J, A B Maier (13318254), Jahn, Gerhard, Kern, F, Samson, S, Griffiths, Paul, Caruso Calogero, K Hamprecht (16139369), Beatrix Grubeck-Loebenstein, Caruso, C, Samson, Sandrine, Moss, Paul; id_orcid, A Akbar (12141924), M Wills (13757002), A Larbi (16139378), Arne Akbar, Strindhall, Jan, Tamas Fülöp, Fülöp Tamas, Willis, Mark, Trannoy, Emanuelle, E Derhovanessian (16139360), D Macallan (16139381), Maier, AB, Akbar,A, Wills, M., Koch Sven D, Moss, P, Larbi,A, Derhovanessian, Evelyna, Trannoy Emanuelle, G Jahn (16139372), Macallan,D, Derhovanessian, E, Klaus Hamprecht, Kern, Florian, Hamprecht Klaus, Beverley,P, Trannoy, E, Larbi Anis, Jahn, G, Samson Sandrine, Graham Pawelec, Macallan, D, Hamprecht,K, Moss,P, Strindhall, Jan,, Beverley, P, Griffiths Paul, Hamprecht, K, Larbi, A, Paul Moss, Maier, Andrea B, Wills, Mark, Maier Andrea B, Macallan, Derek, Grubeck-Loebenstein, Beatrix, Sandrine Samson, Emanuelle Trannoy, Peter Beverley, Kern,F, Jahn Gerhard, Anis Larbi, P Beverley (16139354), Florian Kern, Kern Florian, Gerhard Jahn, Wills, M, Fülöp, Tamas, Koch, SD, Wills Mark, Moss, Paul, Beverley, Peter, Jan Strindhall, Derhovanessian Evelyna, Grubeck-Loebenstein Beatrix, Maier, Andrea B.; id_orcid, Koch, Sven D., Akbar, Arne, Strindhall Jan, S Samson (16139384), T Fulop (16139363), Derek Macallan, Fülöp, T, Mark Wills, B Grubeck-Loebenstein (16139366), P Griffiths (7757690), Evelyna Derhovanessian, Koch, Sven D, Grubeck Loebenstein, B, C Caruso (16139357), Andrea B Maier, E Trannoy (16139390), G Pawelec (16139351), P Moss (7787393), Larbi, Anis, Calogero Caruso, Pawelec Graham, Akbar Arne, Beverley Peter, Paul Griffiths, Moss Paul, Florian Kern (4461943), J Strindhall (16139387), Griffiths, P, Macallan Derek, Caruso, Calogero, Hamprecht, Klaus   +115 more
core   +3 more sources

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Letermovir prophylaxis for cytomegalovirus reactivation in children who underwent hematopoietic stem cell transplantation: A single-institute experience in Taiwan

Journal of Microbiology, Immunology and Infection, 2022
From January 2019 to May 2021, 11 children underwent allogeneic stem cell transplantation at our institute. Four of them received letermovir for cytomegalovirus prophylaxis.
Chao-Neng Cheng, Sin-Syue Li, Yun-Hsuan Yeh, Ching-Fen Shen, Jiann-Shiuh Chen   +4 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source