Microbiology Spectrum, 2016 ABSTRACTCytomegalovirus (CMV), the largest of the herpesviruses, causes a wide range of clinical syndromes, from asymptomatic infection to severe disease in immunocompromised hosts. Laboratory methods for diagnosis include molecular testing, antigenemia, culture, serology, and histopathology.
M Veronica, Dioverti +1 more
+7 more sources
Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation [PDF]
, 2014 NKG2D plays a major role in controlling immune responses through the regulation of natural killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct ligands (the MHC Class I polypeptide-related sequences (MIC) A ...
A Dolan +98 more
core +21 more sources
Cytomegalovirus infection and gastric emptying [PDF]
, 1992 Gastrointestinal infection due to cytomegalovirus occurs frequently in liver transplant recipients. Upper gastrointestinal cytomegalovirus infection is associated with subjective complaints of nausea, a sense of abdominal fullness, and occasionally ...
Chien, MC +4 more
core +1 more source
Severe cytomegalovirus gastritis during natalizumab-mediated immunosuppression [PDF]
, 2017 We report a 35-year-old female receiving natalizumab as monotherapy for multiple sclerosis who subsequently developed severe cytomegalovirus gastritis.
Hassan, Adil +3 more
core +2 more sources
Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]
, 2015 Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca +6 more
core +2 more sources
Impact of sequence variation in the ul128 locus on production of human cytomegalovirus in fibroblast and epithelial cells [PDF]
, 2013 The human cytomegalovirus (HCMV) virion envelope contains a complex consisting of glycoproteins gH and gL plus proteins encoded by the UL128 locus (UL128L): pUL128, pUL130, and pUL131A.
A. J. Davison +87 more
core +2 more sources
Microneutralization of Cytomegalovirus [PDF]
Journal of Infectious Diseases, 1980 A simple microneutralization test for cytomegalovirus (CMV) is presented. Using a laboratory adapted stock virus, definite results were obtained after 10 days. All patients with primary CMV infection showed an antibody rise and/or seroconversion; however, neutralizing antibody appeared only seven weeks after the onset of clinical symptoms.
Stalder, Hans, Ehrensberger, Alice
openaire +3 more sources
Estimation of the worldwide seroprevalence of cytomegalovirus : a systematic review and meta-analysis [PDF]
, 2019 Cytomegalovirus (CMV) infection does not usually produce symptoms when it causes primary infection, reinfection, or reactivation because these three types of infection are all controlled by the normal immune system.
Anderholm +31 more
core +2 more sources
Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]
, 2019 Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang +8 more
core +1 more source
Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]
, 1994 The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Koszinowski, Ulrich H. +4 more
core +1 more source