Results 241 to 250 of about 190,009 (311)

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

open access: yesInternational Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg   +9 more
wiley   +1 more source

Burden and Correlates of Multiple Chronic Infections and Their Associations With Cancer Incidence in Chinese Adults: A Large Case‐Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang   +212 more
wiley   +1 more source

Acute kidney injury, secondary to valacyclovir use during pregnancy for the prevention of fetal cytomegalovirus infection

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract High dose valacyclovir treatment of pregnant women has become a common treatment for primary CMV infection, to prevent vertical transmission to the fetus. We present a case of a healthy young pregnant female with primary CMV infection during the first trimester who was diagnosed with acute kidney injury secondary to valacyclovir treatment ...
Jason Brafman   +3 more
wiley   +1 more source

Zinc Finger E‐Box Binding Homeobox 1 Mediates Alcohol‐Induced Liver Disease

open access: yesiNew Medicine, EarlyView.
Alcohol intake leads to the upregulation of ZEB1, which activates the YAP‐IL‐1β/MCP‐1 pathway, resulting in the activation of liver inflammation and the induction of hepatocyte apoptosis. ABSTRACT Hepatitis resulting from alcoholic liver disease (ALD) is an important risk factor for liver cancer. It is essential to understand the role of ALD to prevent
Boyu Zhang   +5 more
wiley   +1 more source

Seroprevalence of human cytomegalovirus in blood donors. [PDF]

open access: yesGMS Hyg Infect Control
Kanna ALK   +3 more
europepmc   +1 more source

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