The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg +9 more
wiley +1 more source
Erratum in: Host Immune Response and Associated Clinical Features in a Primary Cytomegalovirus Eye Infection Model Using Anterior Chamber Inoculation. [PDF]
europepmc +1 more source
Comparison between enzyme-linked immunospot assay and intracellular cytokine flow cytometry assay of cytomegalovirus-specific T-cell response in healthy participants. [PDF]
Klinmalai C +4 more
europepmc +1 more source
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang +212 more
wiley +1 more source
No substantial causal effect of genetic liability to viral infections on subacute thyroiditis: A large-scale Mendelian randomization analysis. [PDF]
Zeng S, Cheng W.
europepmc +1 more source
Abstract High dose valacyclovir treatment of pregnant women has become a common treatment for primary CMV infection, to prevent vertical transmission to the fetus. We present a case of a healthy young pregnant female with primary CMV infection during the first trimester who was diagnosed with acute kidney injury secondary to valacyclovir treatment ...
Jason Brafman +3 more
wiley +1 more source
Postnatal cytomegalovirus infection and bronchopulmonary dysplasia in very low birth weight infants: Influence of diagnostic criteria and viral load in a propensity score-matched cohort study. [PDF]
Qiao Z, Bao Y, Zhu J.
europepmc +1 more source
Zinc Finger E‐Box Binding Homeobox 1 Mediates Alcohol‐Induced Liver Disease
Alcohol intake leads to the upregulation of ZEB1, which activates the YAP‐IL‐1β/MCP‐1 pathway, resulting in the activation of liver inflammation and the induction of hepatocyte apoptosis. ABSTRACT Hepatitis resulting from alcoholic liver disease (ALD) is an important risk factor for liver cancer. It is essential to understand the role of ALD to prevent
Boyu Zhang +5 more
wiley +1 more source
Cytomegalovirus and Aging-How Can the Field Move Forward? [PDF]
Boeckh M, Corey L.
europepmc +1 more source
Seroprevalence of human cytomegalovirus in blood donors. [PDF]
Kanna ALK +3 more
europepmc +1 more source

