Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results From a Phase 3 Randomized Clinical Trial. [PDF]
Clin Infect Dis, 2022 Background Therapies for refractory cytomegalovirus infections (with or without resistance [R/R]) in transplant recipients are limited by toxicities. Maribavir has multimodal anti-cytomegalovirus activity through the inhibition of UL97 protein kinase ...
Avery RK +18 more
europepmc +2 more sources
Advances in the Development of Therapeutics for Cytomegalovirus Infections. [PDF]
J Infect Dis, 2020 The development of therapeutics for cytomegalovirus (CMV) infections, while progressing, has not matched the pace of new treatments of human immunodeficiency virus (HIV) infections; nevertheless, recent developments in the treatment of CMV infections ...
Acosta E +9 more
europepmc +2 more sources
Clinical Diagnostic Testing for Human Cytomegalovirus Infections. [PDF]
J Infect Dis, 2020 Human cytomegalovirus (HCMV) infections are among the most common complications arising in transplant patients, elevating the risk of various complications including loss of graft and death.
Razonable RR +8 more
europepmc +2 more sources
Antiviral Agents as Therapeutic Strategies Against Cytomegalovirus Infections. [PDF]
Viruses, 2019 Cytomegalovirus (CMV) is a threat to human health in the world, particularly for immunologically weak patients. CMV may cause opportunistic infections, congenital infections and central nervous system infections. CMV infections are difficult to treat due
Chen SJ, Wang SC, Chen YC.
europepmc +2 more sources
Prevalence of cytomegalovirus and BK polyoma virus infection in post-renal transplant patients in a tertiary care centre in South India [PDF]
Journal of Nephropathology, 2017 Background: Viral infections are a significant cause of graft loss and dysfunction in kidney transplant recipients. Cytomegalovirus and BK polyomavirus have often been explained as the most common viral etiological agents.
Kevin Manuel +4 more
doaj +1 more source
Frontiers in Medicine, 2022 BackgroundTo observe and compare the efficacy of 2% ganciclovir eye drops in the treatment of Posner-Schlossman Syndrome relapses with/without cytomegalovirus intraocular reactivation.MethodsA prospective cohort study enrolling 101 patients diagnosed ...
Qilian Sheng +11 more
doaj +1 more source
Gastric Perforation in a 60-Year-Old Woman with CMV Gastritis and Amphetamine Abuse Led to Death
Case Reports in Gastroenterology, 2022 Gastric perforation as a multi-etiological disease is a full-thickness injury of the stomach wall. In this case report, we presented a 60-year-old woman with a history of suicidal behavior referred to the emergency unit with a decreased level of ...
Fatemeh Khajeh +5 more
doaj +1 more source
Transplantology, 2021 Immunosuppressive therapy reduces the risk for allograft rejection but leaves recipients susceptible to infections. Cytomegalovirus (CMV) is one of the most frequent causes for infection after transplantation and increases the risk for allograft ...
Rita Nogueiras-Álvarez +4 more
doaj +1 more source
Primary immunodeficiency screening in an infant with cytomegalovirus disease reveals HIV infection [PDF]
Folia Medica, 2023 Cytomegalovirus is widely spread worldwide, and it is not uncommon for it to complicate the congenital human immunodeficiency virus (HIV) disease as an acquired or congenital coinfection.
Hasan Burnusuzov +3 more
doaj +3 more sources
Pathogenesis of human cytomegalovirus in the immunocompromised host
Nature Reviews Microbiology, 2021 Human cytomegalovirus (HCMV) is a herpesvirus that infects ~60% of adults in developed countries and more than 90% in developing countries. Usually, it is controlled by a vigorous immune response so that infections are asymptomatic or symptoms are mild ...
P. Griffiths, M. Reeves
semanticscholar +1 more source