Advanced Science, EarlyView.βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
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Open Forum Infect Dis, 2023 Anastasopoulou A +8 more
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Alteration of host defense mechanisms by murine cytomegalovirus infection [PDF]
, 1977 D K Kelsey +3 more
openalex +1 more source
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Advanced Science, EarlyView.The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
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Гинекология, 2014 The article presents the results of simultaneous clinical multicenter controlled study of comparative assessment of therapeutic efficacy, safety and tolerability Panavir, solution for intravenous injection of 0,04 mg/ml with the Standardl human ...
V N Prilepskaya +2 more
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Challenges, Recent Advances and Perspectives in the Treatment of Human Cytomegalovirus Infections. [PDF]
Trop Med Infect Dis, 2022 Chen SJ, Wang SC, Chen YC.
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Cytomegalovirus Infection in the North West of England: A Report on a Two-year Study [PDF]
, 1970 Gary Walker, J. O'H. Tobin
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Advanced Science, EarlyView.Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
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