Results 11 to 20 of about 3,451,157 (398)
Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results From a Phase 3 Randomized Clinical Trial. [PDF]
Clin Infect Dis, 2022 Background Therapies for refractory cytomegalovirus infections (with or without resistance [R/R]) in transplant recipients are limited by toxicities. Maribavir has multimodal anti-cytomegalovirus activity through the inhibition of UL97 protein kinase ...
Avery RK +18 more
europepmc +2 more sources
Advances in the Development of Therapeutics for Cytomegalovirus Infections. [PDF]
J Infect Dis, 2020 The development of therapeutics for cytomegalovirus (CMV) infections, while progressing, has not matched the pace of new treatments of human immunodeficiency virus (HIV) infections; nevertheless, recent developments in the treatment of CMV infections ...
Acosta E +9 more
europepmc +2 more sources
Clinical Diagnostic Testing for Human Cytomegalovirus Infections. [PDF]
J Infect Dis, 2020 Human cytomegalovirus (HCMV) infections are among the most common complications arising in transplant patients, elevating the risk of various complications including loss of graft and death.
Razonable RR +8 more
europepmc +2 more sources
Antiviral Agents as Therapeutic Strategies Against Cytomegalovirus Infections. [PDF]
Viruses, 2019 Cytomegalovirus (CMV) is a threat to human health in the world, particularly for immunologically weak patients. CMV may cause opportunistic infections, congenital infections and central nervous system infections. CMV infections are difficult to treat due
Chen SJ, Wang SC, Chen YC.
europepmc +2 more sources
Pathogenesis of human cytomegalovirus in the immunocompromised host
Nature Reviews Microbiology, 2021 Human cytomegalovirus (HCMV) is a herpesvirus that infects ~60% of adults in developed countries and more than 90% in developing countries. Usually, it is controlled by a vigorous immune response so that infections are asymptomatic or symptoms are mild ...
P. Griffiths, M. Reeves
semanticscholar +1 more source
Congenital Cytomegalovirus Infection [PDF]
Ochsner Journal, 2019 Background: Congenital cytomegalovirus (cCMV) is the leading cause of nongenetic congenital hearing loss in much of the world and a leading cause of neurodevelopmental disabilities. Infected babies can be born to women who are seropositive and seronegative prior to pregnancy, and the incidence is approximately 0.6%-0.7% in the United States.
Monika L, Dietrich, John S, Schieffelin
openaire +2 more sources
Human Cytomegalovirus: detection of congenital and perinatal infection in Argentina [PDF]
, 2004 BACKGROUND: Human cytomegalovirus (CMV) is one of the most commonly found agents of congenital infections. Primary maternal infection is associated with risk of symptomatic congenital diseases, and high morbidity is frequently associated with very low ...
Alicia Alonso +25 more
core +3 more sources
Placental Cytomegalovirus Infection [PDF]
Archives of Pathology & Laboratory Medicine, 2018 In the United States, cytomegalovirus is the most common congenital viral infection and the number 1 cause of nonhereditary sensorineural hearing loss. The vast majority of infants may be asymptomatic, especially if cytomegalovirus is contracted later in the pregnancy, and some symptoms may have a delayed onset.
Kaleigh, Lindholm, Mary, O'Keefe
openaire +2 more sources
F1000Research, 2018 Congenital cytomegalovirus infection is a major cause of central nervous system and sensory impairments that affect cognition, motor function, hearing, language development, vestibular function, and vision.
Robert F. Pass, Ravit Arav-Boger
doaj +1 more source
Infection of human cytomegalovirus in cultured human gingival tissue. [PDF]
, 2006 BackgroundHuman cytomegalovirus (HCMV) infection in the oral cavity plays an important role in its horizontal transmission and in causing viral-associated oral diseases such as gingivitis.
Chu, Alice +5 more
core +3 more sources