Results 11 to 20 of about 3,288,372 (337)

Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results From a Phase 3 Randomized Clinical Trial. [PDF]

open access: yesClin Infect Dis, 2022
Background Therapies for refractory cytomegalovirus infections (with or without resistance [R/R]) in transplant recipients are limited by toxicities. Maribavir has multimodal anti-cytomegalovirus activity through the inhibition of UL97 protein kinase ...
Avery RK   +18 more
europepmc   +2 more sources

Advances in the Development of Therapeutics for Cytomegalovirus Infections. [PDF]

open access: yesJ Infect Dis, 2020
The development of therapeutics for cytomegalovirus (CMV) infections, while progressing, has not matched the pace of new treatments of human immunodeficiency virus (HIV) infections; nevertheless, recent developments in the treatment of CMV infections ...
Acosta E   +9 more
europepmc   +2 more sources

Clinical Diagnostic Testing for Human Cytomegalovirus Infections. [PDF]

open access: yesJ Infect Dis, 2020
Human cytomegalovirus (HCMV) infections are among the most common complications arising in transplant patients, elevating the risk of various complications including loss of graft and death.
Razonable RR   +8 more
europepmc   +2 more sources

Antiviral Agents as Therapeutic Strategies Against Cytomegalovirus Infections. [PDF]

open access: yesViruses, 2019
Cytomegalovirus (CMV) is a threat to human health in the world, particularly for immunologically weak patients. CMV may cause opportunistic infections, congenital infections and central nervous system infections. CMV infections are difficult to treat due
Chen SJ, Wang SC, Chen YC.
europepmc   +2 more sources

Prevalence of cytomegalovirus and BK polyoma virus infection in post-renal transplant patients in a tertiary care centre in South India [PDF]

open access: yesJournal of Nephropathology, 2017
Background: Viral infections are a significant cause of graft loss and dysfunction in kidney transplant recipients. Cytomegalovirus and BK polyomavirus have often been explained as the most common viral etiological agents.
Kevin Manuel   +4 more
doaj   +1 more source

2% Ganciclovir Eye Drops Control Posner-Schlossman Syndrome Relapses With/Without Cytomegalovirus Intraocular Reactivation

open access: yesFrontiers in Medicine, 2022
BackgroundTo observe and compare the efficacy of 2% ganciclovir eye drops in the treatment of Posner-Schlossman Syndrome relapses with/without cytomegalovirus intraocular reactivation.MethodsA prospective cohort study enrolling 101 patients diagnosed ...
Qilian Sheng   +11 more
doaj   +1 more source

Gastric Perforation in a 60-Year-Old Woman with CMV Gastritis and Amphetamine Abuse Led to Death

open access: yesCase Reports in Gastroenterology, 2022
Gastric perforation as a multi-etiological disease is a full-thickness injury of the stomach wall. In this case report, we presented a 60-year-old woman with a history of suicidal behavior referred to the emergency unit with a decreased level of ...
Fatemeh Khajeh   +5 more
doaj   +1 more source

A Retrospective Review of Calcineurin Inhibitors’ Impact on Cytomegalovirus Infections in Lung Transplant Recipients

open access: yesTransplantology, 2021
Immunosuppressive therapy reduces the risk for allograft rejection but leaves recipients susceptible to infections. Cytomegalovirus (CMV) is one of the most frequent causes for infection after transplantation and increases the risk for allograft ...
Rita Nogueiras-Álvarez   +4 more
doaj   +1 more source

Pathogenesis of human cytomegalovirus in the immunocompromised host

open access: yesNature Reviews Microbiology, 2021
Human cytomegalovirus (HCMV) is a herpesvirus that infects ~60% of adults in developed countries and more than 90% in developing countries. Usually, it is controlled by a vigorous immune response so that infections are asymptomatic or symptoms are mild ...
P. Griffiths, M. Reeves
semanticscholar   +1 more source

Treatment of congenital cytomegalovirus infection [PDF]

open access: yesClinical and Experimental Pediatrics, 2023
Congenital cytomegalovirus (CMV) is the most common cause of congenital infection worldwide, the most common nongenetic cause of sensorineural hearing loss in children, and a cause of neurodevelopmental disorders in the brain.
Gyu Hong Shim
doaj   +1 more source

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