Novel Cost-Efficient Graphene-Based Impedance Biosensor for the Analysis of Viral Cytopathogenicity and the Effect of Antiviral Drugs [PDF]
Biosensors become increasingly relevant for medical diagnostics, pharmaceutical industry, and environmental technology, for example, to test new drugs easily and reliably or to detect cell growth in changing environmental conditions. Novel materials like graphene are promising candidates to produce biosensors on an industrial scale by means of printing
Schultz, Anke+6 more
openaire +5 more sources
Interferons, properties and applications [PDF]
The main theme of this thesis is the clinical evaluation of interferon. From the biology of the interferon system and animal experiments it can be expected that exogenous interferon will exert its optimum effect when used to prevent acute infections or ...
Schellekens, H. (Huub)+1 more
core +7 more sources
Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide [PDF]
Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial ...
Abudureyimu, A+6 more
core +1 more source
Deficiency of immunity to poliovirus type 3: a lurking danger? [PDF]
Background: Europe was certified to be polio-free in 2002 by the WHO. However, wild polioviruses remain endemic in India, Pakistan, Afghanistan, and Nigeria, occasionally causing polio outbreaks, as in Tajikistan in 2010.
Doerr, Hans W.+3 more
core +2 more sources
Acute BVDV infection inhibits expression of interferon-stimulated genes during pregnancy recognition in bovine endometrium [PDF]
Bovine viral diarrhea virus (BVDV) can evade host detection by downregulation of interferon signaling pathways. Infection of cows with noncytopathic (ncp) BVDV can cause early embryonic mortality. Upregulation of type I interferon stimulated genes (ISGs)
Abudureyimu, A+6 more
core +1 more source
Attempts to isolate virus from human brain tumors [PDF]
In order to study the viral etiology of human brain tumors, attempts were made to isolate cytopathogenic agents from human brain tumors by the tissue culture of tumor tissues and by the mixed culture of tumor tissues with HeLa cells.
Yabe, Yoshiro
core +1 more source
Chlorogenic Compounds from Coffee Beans Exert Activity against Respiratory Viruses [PDF]
Chlorogenic acids are secondary metabolites in diverse plants. Some chlorogenic acids extracted from traditional medicinal plants are known for their healing properties, e.g., against viral infections.
Benedetti, Fabio+8 more
core +1 more source
Differential expression of chemokines and their receptors in adult and neonatal macrophages infected with human or avian influenza viruses [PDF]
In 1997, avian influenza virus H5N1 was transmitted directly from chicken to human and resulted in a severe disease that had a higher mortality rate in adults than in children.
Cheung, CY+5 more
core +1 more source
Helicobacter pullorum cytolethal distending toxin targets vinculin and cortactin and triggers formation of lamellipodia in intestinal epithelial cells [PDF]
Helicobacter pullorum, a bacterium initially isolated from poultry, has been associated with human digestive disorders. However, the factor responsible for its cytopathogenic effects on epithelial cells has not been formally identified.
Aboubacar, A.+10 more
core +1 more source
Advances in the design and development of oncolytic measles viruses. [PDF]
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian+2 more
core +1 more source