Advances in the design and development of oncolytic measles viruses. [PDF]
, 2015 A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian +2 more
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A cytopathogenic effect of influenza virus (PR-8 strain) for mouse fibroblastic (L) cells in vitro.
Journal of Immunology, 1960 A lytic action of influenza A virus (PR-8) for L cells in vitro has been demonstrated which occurs only with large amounts of infectious virus. This action of the virus involves attachment, penetration, and a limited form of viral replication which ...
D. Smith, H. Morgan
semanticscholar +1 more source
Infection of human embryonic skin-muscle tissue culture cells with adenovirus type 12 [PDF]
, 1966 ,The effect of infection of human embryonic skin-muscle cell cultures with adenovirus type 12 has been studied. When maintained in YLE containing 20 per cent bovine serum, human embryonic skin-muscle tissue culture cells developed little or no ...
Murakami, Sakae, Yabe, Yoshiro
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Interactions of human microglia cells with Japanese encephalitis virus [PDF]
, 2017 Japanese encephalitis virus (JEV) is a neurotropic flavivirus causing mortality and morbidity in humans. Severe Japanese encephalitis cases display strong inflammatory responses in the central nervous system and an accumulation of viral particles in ...
Filgueira, Luis +6 more
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neutrophils are on the payroll [PDF]
, 2015 Viral hemorrhagic fever caused by hantaviruses is an emerging infectious disease for which suitable treatments are not available. In order to improve this situation a better understanding of hantaviral pathogenesis is urgently required.
Krüger, Detlev H. +2 more
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Senecavirus A (SVA) in finishing swine: diagnosis and viral isolation
, 2020 Senecavirus A (SVA) has been a problem in Brazil since the end of 2014. The infections caused by SVA have disrupted the productive chain in Brazil, as it can be confused with foot-and-mouth disease. Although, the virus has remained endemic in the country,
M. Muller +3 more
semanticscholar +1 more source
Bird's eye view of natural products for the development of new anti-HIV agents: Understanding from a therapeutic viewpoint. [PDF]
Animal Model Exp MedDevelopment of pharmaceutical drugs to cure HIV is crucial due to the current widespread epidemic. Nucleosides are the most effective anti‐HIV drugs, but their high toxicity and drug resistance limit their use. This review focuses on potential natural medicinal products for treating and managing HIV and AIDS.
Al Amin M +12 more
europepmc +2 more sources
Cellular mRNAs access second ORFs using a novel amino acid sequence-dependent coupled translation termination-reinitiation mechanism [PDF]
, 2014 Polycistronic transcripts are considered rare in the human genome. Initiation of translation of internal ORFs of eukaryotic genes has been shown to use either leaky scanning or highly structured IRES regions to access initiation codons.
Croft, Wayne D. +4 more
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Apigenin Restricts FMDV Infection and Inhibits Viral IRES Driven Translational Activity
Viruses, 2015 Foot-and-mouth disease (FMD) is a highly contagious disease of domestic and wild ruminants that is caused by FMD virus (FMDV). FMD outbreaks have occurred in livestock-containing regions worldwide.
Suhong Qian +6 more
semanticscholar +1 more source
Heterologous prime-boost vaccination with H3N2 influenza viruses of swine favors cross-clade antibody responses and protection [PDF]
, 2017 The emergence of multiple novel lineages of H1 and H3 influenza A viruses in swine has confounded control by inactivated vaccines. Because of substantial genetic and geographic heterogeneity among circulating swine influenza viruses, one vaccine strain ...
Claes, Gerwin +8 more
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