Results 101 to 110 of about 1,653,701 (332)

Etymologia: Histoplasma capsulatum

open access: yesEmerging Infectious Diseases, 2021
Monika Mahajan
doaj   +1 more source

ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability

open access: yeseLife
Autophagy-related gene 6 (ATG6) plays a crucial role in plant immunity. Nonexpressor of pathogenesis-related genes 1 (NPR1) acts as a signaling hub of plant immunity. However, the relationship between ATG6 and NPR1 is unclear.
Baihong Zhang   +9 more
doaj   +1 more source

SHuffle, a novel Escherichia coli protein expression strain capable of correctly folding disulfide bonded proteins in its cytoplasm

open access: yesMicrobial Cell Factories, 2012
BackgroundProduction of correctly disulfide bonded proteins to high yields remains a challenge. Recombinant protein expression in Escherichia coli is the popular choice, especially within the research community.
J. Lobstein   +5 more
semanticscholar   +1 more source

Direct introduction of cloned DNA into the sea urchin zygote nucleus, and fate of injected DNA [PDF]

open access: yes, 1988
A method is described for microinjection of cloned DNA into the zygote nucleus of Lytechinus variegatus. Eggs of this species are unusually transparent, facilitating visual monitoring of the injection process.
Britten, Roy J.   +3 more
core  

Automated segmentation of tissue images for computerized IHC analysis [PDF]

open access: yes, 2010
This paper presents two automated methods for the segmentation ofimmunohistochemical tissue images that overcome the limitations of themanual approach aswell as of the existing computerized techniques.
A. Acquaviva   +43 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension. [PDF]

open access: yes, 2017
Objective:Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p)YAP1 in prostate cancer (PCa) tumorigenesis, we investigated their expression in ...
Collak, Filiz Kisaayak   +4 more
core  

Spatial mapping reveals multi-step pattern of wound healing in Physarum polycephalum

open access: yes, 2017
Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a common ...
Alim, Karen   +2 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

A machine learning model for predicting fertilization following short‐term insemination using embryo images

open access: yesReproductive Medicine and Biology
Purpose This study established a machine learning model (MLM) trained on embryo images to predict fertilization following short‐term insemination for early rescue ICSI and compared its predictive performance with the embryologist's manual classification.
Masato Saito   +10 more
doaj   +1 more source

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