Results 121 to 130 of about 1,366,500 (340)
Dynamic structure of the cytoplasm
The cytoplasm is a dense and complex milieu in which a plethora of biochemical reactions occur. Its structure is not understood so far, albeit being central to cellular functioning.
Kim, Hyojun, Delarue, Morgan
core +1 more source
Cellular Hydraulics Suggests a Poroelastic Cytoplasm Rheology [PDF]
, 2013 The cytoplasm represents the largest part of the cell by volume and hence its rheology sets the rate at which cellular shape change can occur. Recent experimental evidence suggests that cytoplasmic rheology can be described using a poroelastic ...
Mahadevan, Lakshminarayanan +8 more
core
Protein diffusion in mammalian cell cytoplasm.
PLoS ONE, 2011 We introduce a new method for mesoscopic modeling of protein diffusion in an entire cell. This method is based on the construction of a three-dimensional digital model cell from confocal microscopy data.
Thomas Kühn +7 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Selection with Gene-Cytoplasm Interactions. II. Maintenance of Gynodioecy
, 1985 Gynodioecy is apparently frequently inherited through gene-cytoplasm interactions. General conditions for the protectedness of gene-cytoplasm polymorphisms for a biallelic model with two cytoplasm types were obtained previously, and these are applied to ...
Ross, M. D., Gregorius, H. R.
core +1 more source
Cell, 2013 SUMMARY Period determination in the mammalian circadian clock involves the turnover rate of the repressors, CRY and PER. Here we show that CRY ubiquitination engages two competing E3 ligase complexes that either lengthen or shorten circadian period in ...
Seung-Hee Yoo +15 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Biotechnology & Biotechnological Equipment, 2019 Cytoplasmic genomes affect various phenotypes, including abiotic stress responses, through interaction with nuclear genomes in plants. We focused on the effects of cytoplasmic substitution on germination and seedling growth in combinations with ...
Shotaro Takenaka +2 more
doaj +1 more source
Diffusion, Crowding & Protein Stability in a Dynamic Molecular Model of the Bacterial Cytoplasm
PLoS Comput. Biol., 2010 A longstanding question in molecular biology is the extent to which the behavior of macromolecules observed in vitro accurately reflects their behavior in vivo.
S. McGuffee, A. Elcock
semanticscholar +1 more source