Results 71 to 80 of about 1,426,971 (334)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Sex-specific alterations in creatine metabolism in cellular compartments of peripheral blood leukocytes in type 1 diabetes

open access: yesAIMS Bioengineering
The creatine (Cr)/creatine kinase (CK) system plays a crucial role in cellular energy metabolism, glucose control, and the immune response. This study aimed to investigate this system in the peripheral blood leukocytes (PBL) of Armenians with type 1 ...
Nina Alchujyan   +6 more
doaj   +1 more source

Promiscuity of the Euonymus Carbohydrate-Binding Domain

open access: yesBiomolecules, 2012
Plants synthesize small amounts of carbohydrate-binding proteins on exposure to stress. For example, on exposure to drought, high salt, wounding and by treatment with some plant hormones or by pathogen attack. In contrast to the ‘classical’ plant lectins
Els J.M. Van Damme, Elke Fouquaert
doaj   +1 more source

Evidence for prelocalization of cytoplasmic factors affecting gene activation in early embryogenesis [PDF]

open access: yes, 1965
Differentiation begins early in embryogenesis as different genes become active in different cells. Within the closed system of the early embryo, equal genomes thus direct the creation of diverse cell types.
Allfrey, V. G.   +4 more
core  

Spatial mapping reveals multi-step pattern of wound healing in Physarum polycephalum

open access: yes, 2017
Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a common ...
Alim, Karen   +2 more
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Implication of mating type and cytoplasm factors in asymmetric distribution of two types of monokaryons recovered from dikaryons in Lentinula edodes

open access: yes浙江大学学报. 农业与生命科学版, 2008
The genetics background for the phenomenon of significantly distortion to the expected 1∶1 ratio of the two constitute nucleus in Lentinula edodes was investigated after protoplast monokaryotization.
CHENG Shui-ming, LIN Fan-xue, XU Chun
doaj   +1 more source

Threshold estimation based on local minima for nucleus and cytoplasm segmentation

open access: yesBMC Medical Imaging, 2022
Background Image segmentation is the process of partitioning an image into separate objects or regions. It is an essential step in image processing to segment the regions of interest for further processing.
Simeon Mayala, Jonas Bull Haugsøen
doaj   +1 more source

Millisecond single-molecule localization microscopy combined with convolution analysis and automated image segmentation to determine protein concentrations in complexly structured, functional cells, one cell at a time [PDF]

open access: yes, 2015
We present a single-molecule tool called the CoPro (Concentration of Proteins) method that uses millisecond imaging with convolution analysis, automated image segmentation and super-resolution localization microscopy to generate robust estimates for ...
Leake, Mark C., Wollman, Adam J. M.
core   +2 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy