Results 121 to 130 of about 272,495 (294)

Granular acute lymphocytic leukemia : a case report and literature review

Discover Oncology
Acute lymphoblastic leukemia (ALL) is a malignant disease characterized by the clonal proliferation of precursor lymphoblasts in the bone marrow. Granular acute lymphoblastic leukemia (G-ALL) is a rare subtype of ALL, primarily associated with B-cell ...
Yike Tian, Ping Huang, Mi Jiang, Jing Wu, Wei Cai   +4 more
doaj   +1 more source

Investigations into Xpat, a novel gene expressed in the germ plasm and primordial germ cells of Xenopus laevis [PDF]

To determine the expression pattern of XPAT (Xenopus primordial germ cell associated transcript) protein in Xenopus oocytes, XPAT-GFP fusion proteins were generated.
McCormick, Rachel Jacqueline
core  

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

Advanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan, Xinzhe Feng, Chuanju Liu, Jianfei Tong, Zhi Li, Chenxu Liu, Yutong Dong, Chen Meng, Yihong Xu, Weidong Xu   +9 more
wiley   +1 more source

Stress Granules Contain Rbfox2 with Cell Cycle-related mRNAs

, 2017
Rbfox RNA-binding proteins play important roles in the regulation of alternative pre-mRNA splicing, but their role in other gene regulatory mechanisms is not well understood. Here, we show that Rbfox2 is a novel constituent of cytoplasmic stress granules,
Kee K. Kim, Sunkyung Choi, Yong-Eun Kim, Robert S. Adelstein, Sachiyo Kawamoto, Su-Hyung Park, Siyeo Lee, Chungoo Park   +7 more
core   +1 more source

Proteins that contain a functional Z-DNA-binding domain localize to cytoplasmic stress granules [PDF]

, 2013
Long double-stranded RNA may undergo hyper-editing by adenosine deaminases that act on RNA (ADARs), where up to 50% of adenosine residues may be converted to inosine.
Scadden, A. D. J., Weissbach, Rebekka, Ng, Siew Kit, Ronson, George E.   +3 more
core   +1 more source

Differential Diagnosis of Mucopolysaccharidoses Types I, II, III, IVA, and VI Through Analysis of Leukocytic Inclusions

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mucopolysaccharidoses (MPS) are lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs), which can lead to cytoplasmic alterations in leukocytes. The objective of this study was to characterize leukocyte inclusions in patients with different types of MPS and assess their diagnostic relevance.
Márcio A. W. Melo, Marcelo S. Kertenetzky, Cristina M. Silveira, Maíra M. Ribeiro, Paula F. Medeiros, Gabriela S. Arcanjo   +5 more
wiley   +1 more source

Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD

Acta Neuropathologica Communications
The abnormal aggregation of TDP-43 into cytoplasmic inclusions in affected neurons is a major pathological hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Although TDP-43 is aberrantly accumulated in the neurons of most
Tetsuhiro Ueda, Toshihide Takeuchi, Nobuhiro Fujikake, Mari Suzuki, Eiko N. Minakawa, Morio Ueyama, Yuzo Fujino, Nobuyuki Kimura, Seiichi Nagano, Akio Yokoseki, Osamu Onodera, Hideki Mochizuki, Toshiki Mizuno, Keiji Wada, Yoshitaka Nagai   +14 more
doaj   +1 more source

Multiple Auer Rods in Fine-Needle Aspiration Smears of Medullary Thyroid Carcinoma: An Unusual Finding

International Medical Case Reports Journal, 2020
Maryam Mohammadnia Avval, Perikala Vijayananda Kumar, Fereydoon Dehghani Department of Pathology, Shiraz University of Medical Sciences, Shiraz, IranCorrespondence: Maryam Mohammadnia AvvalDepartment of Pathology, Shiraz University of Medical Sciences ...
Mohammadnia Avval M, Kumar PV, Dehghani F   +2 more
doaj  

Characterization of the extracellular matrix from human and dog umbilical cords

The Anatomical Record, EarlyView.
Abstract The extracellular matrix is important for maintaining tissue morphogenesis and homeostasis; it can also be used as a biomaterial for the production of biological scaffolds. Particularly, the umbilical cord has shown potential in the production of scaffolds for small‐diameter vessels.
Ana Carla Mendonça, Roberta Losi Guembarovski, Carlos Alberto Miqueloto, Alda Fiorina Maria Losi Guembarovski, Caio Garcia Barbosa da Silva, Laís Capelasso Lucas Pinheiro, Phelipe Oliveira Favaron   +6 more
wiley   +1 more source

Germline-specific RNA helicase DDX4 forms cytoplasmic granules in cancer cells and promotes tumor growth

Image files for the research title: "Germline-specific RNA helicase DDX4 forms cytoplasmic granules in cancer cells and promotes tumor growth"THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE
olotu, O (via Mendeley Data)
core   +2 more sources