Results 111 to 120 of about 206,171 (265)

Wolbachia pipientis: bacterial density and unidirectional cytoplasmic incompatibility between infected populations of Aedes albopictus

, 1995
Unidirectional cytoplasmic incompatibility is seen when certain Wolbachia-infected insect populations are crossed. Two hypotheses might explain this phenomenon: superinfections with mutually incompatible strains of Wolbachia producing incompatibility ...
Sinkins, S. P., Braig, H. R., O'Neill, S. L.   +2 more
core   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

Loss of cytoplasmic incompatibility in Wolbachia-infected Aedes aegypti under field conditions.

PLoS Neglected Tropical Diseases, 2019
Wolbachia bacteria are now being introduced into Aedes aegypti mosquito populations for dengue control. When Wolbachia infections are at a high frequency, they influence the local transmission of dengue by direct virus blocking as well as deleterious ...
Perran A Ross, Scott A Ritchie, Jason K Axford, Ary A Hoffmann   +3 more
doaj   +1 more source

Variation in the prevalence of cytoplasmic incompatibility-inducing Wolbachia in the butterfly Eurema hecabe across the Japanese archipelago. Evol Ecol Res 7: 931–942

, 2005
Question: Is the prevalence of cytoplasmic incompatibility-inducing Wolbachia spreading throughout butterfly populations? Hypothesis: Wolbachia are self-promoting intracellular microbes and the infection spreads easily among host populations.
Masato Hiroki, Yoshiomi Kato, Yumiko Ishii   +2 more
core  

Relationships between Wolbachia density and the fidelity of cytoplasmic incompatibility.

, 2020
(A) The relationship between male Wolbachia density and cytoplasmic incompatibility induction when wMel-infected males were exposed to various heatwave treatments.
Jason K. Axford (8137092), Qiong Yang (28822), Kyran M. Staunton (8350977), Ary A. Hoffmann (7443281), Scott A. Ritchie (8139414), Perran A. Ross (7827680), Kelly M. Richardson (7903844)   +6 more
core   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

Advanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin, Ping Zhang, Qing Song, Tao Li, Yuqin Zeng, Ping Chen   +5 more
wiley   +1 more source

Wolbachia Infections in Aedes aegypti Differ Markedly in Their Response to Cyclical Heat Stress.

PLoS Pathogens, 2017
Aedes aegypti mosquitoes infected with Wolbachia bacteria are currently being released for arbovirus suppression around the world. Their potential to invade populations and persist will depend on interactions with environmental conditions, particularly ...
Perran A Ross, Itsanun Wiwatanaratanabutr, Jason K Axford, Vanessa L White, Nancy M Endersby-Harshman, Ary A Hoffmann   +5 more
doaj   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

CI strain_Cytoplasmic Incompatibility

, 2016
Lab collected crossing data for CI strain of Drosophila pandora, used to evaluate Cytoplasmic Incompatibility. Data from two experiments (Jan 2014 and April 2014), showing the number of hatched/unhatched eggs collected and scored, and the number of male ...
Schiffer, Michele, Lee, Siu F., Hoffmann, Ary A., Richardson, Kelly M., Griffin, Philippa C., Michele Schiffer (3361901), Ary A. Hoffmann (7443281), Philippa C. Griffin (7903847), Kelly M. Richardson (7903844), Siu F. Lee (7903850)   +9 more
core   +1 more source

CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Advanced Science, EarlyView.
AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu   +6 more
wiley   +1 more source