Results 141 to 150 of about 420,555 (284)

Hybrid breeding of cauliflower using self-incompatibility and cytoplasmic male sterility

Horticultural Science, 2006
Two self-sterility systems, self-incompatibility (SI) and cytoplasmic male sterility (CMS) were used to verify their suitability for hybrid breeding of cauliflower.
V. Kučera, V. Chytilová, M. Vyvadilová, M. Klíma   +3 more
doaj   +1 more source

Identification of the het-r vegetative incompatibility gene of Podospora anserina as a member of the fast evolving HNWD gene family [PDF]

, 2009
In fungi, vegetative incompatibility is a conspecific non-self recognition mechanism that restricts formation of viable heterokaryons when incompatible alleles of specific het loci interact.
Bastiaans, E., Chevanne, D., Clave, C., Debets, A.J.M., Paoletti, M., Saupe, S.J.   +5 more
core   +3 more sources

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

Advanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan, Natan Roberto de Barros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari   +11 more
wiley   +1 more source

Wolbachia: A biological control strategy against arboviral diseases

Journal of Vector Borne Diseases, 2016
Vector-borne diseases particularly those transmitted by mosquitoes like Dengue are among the leading causes of mortality and morbidity in human population.
Ipsita Mohanty, Animesha Rath, Namita Mahapatra, Rupenangshu K Hazra   +3 more
doaj  

Vector species-specific association between natural Wolbachia infections and avian malaria in black fly populations [PDF]

, 2018
Thanks to the Institute of Biodiversity Animal Health and Comparative Medicine (University of Glasgow) for funding vector traps.Artificial infection of mosquitoes with the endosymbiont bacteria Wolbachia can interfere with malaria parasite development ...
Baldini, Francesco, Bianco, Giovanni, Dale, Maeve, Elmer, Kathryn, Ferguson, Heather M., Helm, Barbara, Ivanova, Yoana, Larcombe, Stephen D., Rae, Fiona, Woodford, Luke   +9 more
core   +4 more sources

One prophage WO gene rescues cytoplasmic incompatibility in Drosophila melanogaster

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance The World Health Organization recommended pilot deployment of Wolbachia-infected mosquitoes to curb viral transmission to humans. Releases of mosquitoes are underway worldwide because Wolbachia can block replication of these pathogenic ...
J. Shropshire, Jungmin On, Emily M. Layton, Helen H. Zhou, Seth R. Bordenstein   +4 more
semanticscholar   +1 more source

Cytoplasmic incompatibility between Old and New World populations of a tramp ant

bioRxiv, 2020
As we enter the Anthropocene, the evolutionary dynamics of species will change drastically, and as yet unpredictably, due to human activity. Already today, increases in global human traffic have resulted in the rapid spread of species to new areas ...
Ç. Ün, E. Schultner, A. Manzano-Marín, Laura V. Flórez, B. Seifert, J. Heinze, J. Oettler   +6 more
semanticscholar   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Comparisons of host mitochondrial, nuclear and endosymbiont bacterial genes reveal cryptic fig wasp species and the effects of Wolbachia on host mtDNA evolution and diversity [PDF]

, 2011
Background Figs and fig-pollinating wasp species usually display a highly specific one-to-one association. However, more and more studies have revealed that the "one-to-one" rule has been broken. Co-pollinators have been reported, but we do not yet know
A Jeyaprakash, A Telschow, A Telschow, AB Ware, AR Rogers, AV Brower, C Kerdelhue, C Lopez-Vaamonde, CA Machado, D Molbo, Da-Wei Huang, DD Shoemaker, DD Shoemaker, DD Shoemaker, E Baudry, E Haine, ER Haine, F Tajima, FM Jiggins, G Michaloud, GD Hurst, Gui Feng, J Rasgon, J Seger, James M Cook, JH Werren, JH Werren, Jin-Hua Xiao, JM Cook, JM Cook, JT Wiebes, JW Ballard, K Tamura, KL Simonsen, L Viljakainen, LL Chen, O Folmer, P Librado, PD Hebert, PD Hebert, S Aris-Brosou, S Kambhampati, SG Compton, SL Dobson, SL O'Neill, SR Bordenstein, T White, TL Whitworth, Xiao-Jing Sun, YQ Peng, YW Li, Z Bouček   +51 more
core   +3 more sources

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source