Results 51 to 60 of about 206,171 (265)

CYTOPLASMIC INCOMPATIBILITY IN POPULATIONS WITH OVERLAPPING GENERATIONS [PDF]

Evolution, 2010
Many insects and other arthropods harbor maternally inherited bacteria inducing "cytoplasmic incompatibility" (CI), reduced egg hatch when infected males mate with uninfected females. CI-causing infections produce a frequency-dependent reproductive advantage for infected females.
openaire   +2 more sources

UNIDIRECTIONAL CYTOPLASMIC INCOMPATIBILITY IN THE MOSQUITO,AEDES ALBOPICTUS [PDF]

Evolution, 1993
Endosymbiont-modulated cytoplasmic incompatibility (CI) is known to occur in several genera of insects includingAedes (Beckett et al., 1978; Trpis et al., 1981), Culex (Barr, 1982; Subbarao, 1982), Drosophila (Hoffmann et al., 1986; Hoffmann and Turelli, 1988; O'Neill and Karr, 1990), Laodelphax (Noda, 1984), Hypera (Hsiao and Hsiao, 1985), Nasonia ...
Srinivas, Kambhampati, Karamjit S, Rai, Stephen J, Burgun   +2 more
openaire   +2 more sources

Wolbachia-induced cytoplasmic incompatibility (CI).

, 2014
Wolbachia-induced cytoplasmic incompatibility (CI).
Arndt Telschow (267225), John H. Werren (254126), Peter Hammerstein (221627), Kirsten Hilgenboecker (555082)   +3 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Wolbachia variability and host effects on crossing type in Culex mosquitoes

, 2005
Wolbachia is a common maternally inherited bacterial symbiont able to induce crossing sterilities known as cytoplasmic incompatibility (CI) in insects1, 2.
Sinkins, Steven P., H. Charles J. Godfray, Godfray, H. Charles J., Lynd, Amy R, Ben L. Makepeace, J. Godfray, H. Charles, Amy R. Lynd, Steven, Andrew, Steven, Andrew R, Julian Parkhill, Sinkins, Steven P, Thomas Walker, Parkhill, Julian, Makepeace, Ben L., Walker, Thomas, Andrew R. Steven, Steven P. Sinkins, Charles, H., Makepeace, Ben L, Steven, Andrew R., Godfray, J., Lynd, Amy, Lynd, Amy R., Godfray, H Charles J   +23 more
core   +1 more source

Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. [PDF]

, 2011
BACKGROUND: Wolbachia are endosymbiotic bacteria that are frequently found in arthropods and nematodes. These maternally inherited bacteria manipulate host reproduction by several mechanisms including cytoplasmic incompatibility (CI).
Yu-Feng Wang, Thomas Walker, Wang Jia-Lin, Liu, Chen, Liu Chen, Chen Liu, Walker, Thomas, Wang, Yu-Feng, Wang Cui-Ping, Zheng Ya, Jia-Lin Wang, Cui-Ping Wang, Wang, Jia-Lin, Walker Thomas, Wang Yu-Feng, Ya Zheng, Zheng, Ya, Wang, Cui-Ping   +17 more
core   +2 more sources

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations

, 2011
Dengue fever is the most important mosquito-borne viral disease of humans with more than 50 million cases estimated annually in more than 100 countries. Disturbingly, the geographic range of dengue is currently expanding and the severity of outbreaks is ...
C. J. McMeniman, Y. Dong, Axford, J, P. Kriesner, Johnson, PH, A. L. Lloyd, Lloyd, AL, Dong, Y, Hoffmann, AA, Dong, Y., Frentiu, F. D., Frentiu, FD, Hoffmann, A. A., S. A. Ritchie, F. D. Frentiu, Walker, Thomas, L. A. Moreira, Lloyd, A. L., O'Neill, SL, J. Axford, Kriesner, P., Moreira, L.A., Leong, Y. S., I. Iturbe-Ormaetxe, Leong, Y.S., McMeniman, CJ, P. H. Johnson, Walker, T, Axford, J., Y. S. Leong, Moreira, L. A., Leong, YS, S. L. O’Neill, Ritchie, SA, O’Neill, S. L., Kriesner, P, Johnson, P.H., O'Neill, S.L., Lloyd, A.L., McMeniman, C. J., Ritchie, S.A., Ritchie, S. A., O'Neill, S. L., T. Walker, Iturbe-Ormaetxe, I., Iturbe-Ormaetxe, I, A. A. Hoffmann, Walker, T., McMeniman, C.J., Moreira, LA, Hoffmann, A.A., Frentiu, F.D., Johnson, P. H.   +52 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source