Results 61 to 70 of about 206,171 (265)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Demographic Variation of Wolbachia Infection in the Endangered Mitchell’s Satyr Butterfly

Insects, 2017
The Mitchell’s satyr, Neonympha mitchellii, is an endangered species that is limited to highly isolated habitats in the northern and southern United States.
Jennifer Fenner, Jennifer Seltzer, Scott Peyton, Heather Sullivan, Peter Tolson, Ryan P. Walsh, JoVonn Hill, Brian A. Counterman   +7 more
doaj   +1 more source

Cytoplasmic incompatibility (CI) between Wolbachia infected and wild type mosquitoes.

, 2016
Cytoplasmic incompatibility (CI) between Wolbachia infected and wild type mosquitoes.
Jyotika Taneja De Bruyne (2150929), Nguyen Van Vinh Chau (75053), Lauren B. Carrington (347465), Scott L. O’Neill (298378), D. Albert Joubert (2150926), Nhat Le Thanh Hoang (2150932), Iñaki Iturbe-Ormaetxe (373563), Thomas Walker (81255), Duong Hue T. Kien (2150923), Cameron P. Simmons (117211)   +9 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Wolbachia affect behavior and possibly reproductive compatibility but not thermoresistance, fecundity, and morphology in a novel transinfected host, Drosophila nigrosparsa

Ecology and Evolution, 2020
Wolbachia, intracellular endosymbionts, are estimated to infect about half of all arthropod species. These bacteria manipulate their hosts in various ways for their maximum benefits.
Matsapume Detcharoen, Wolfgang Arthofer, Francis M. Jiggins, Florian M. Steiner, Birgit C. Schlick‐Steiner   +4 more
doaj   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

From parasite to mutualist: rapid evolution of Wolbachia in natural populations of Drosophila. [PDF]

PLoS Biology, 2007
Wolbachia are maternally inherited bacteria that commonly spread through host populations by causing cytoplasmic incompatibility, often expressed as reduced egg hatch when uninfected females mate with infected males.
Andrew R Weeks, Michael Turelli, William R Harcombe, K Tracy Reynolds, Ary A Hoffmann   +4 more
doaj   +1 more source

Global Dynamics for Competition between Two Wolbachia Strains with Bidirectional Cytoplasmic Incompatibility

Mathematics, 2023
Releasing Wolbachia-infected mosquitoes to suppress or replace wild vector mosquitoes has been carried out in 24 countries worldwide, showing great promise in controlling mosquitoes and mosquito-borne diseases.
Qiming Huang, Lijie Chang, Zhaowang Zhang, Bo Zheng   +3 more
doaj   +1 more source

ATP‐Mediated Bidirectional Communication Between Natural and Artificial Cells for Controlled Bioreactions

Advanced Functional Materials, EarlyView.
Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte, Tsvetomir Ivanov, Leonhard Seufert, Shoupeng Cao, Lucas Caire da Silva, Volker Mailänder, Katharina Landfester   +6 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source