Results 61 to 70 of about 9,534 (270)

Introgression of extranuclear genomes in finite populations: Nucleo-cytoplasmic incompatibility [PDF]

open access: yes, 1985
A ‘two locus two allele’ model is developed with special reference to the introgression of extranuclear genomes between two species of finite size. The model assumes that one locus, coded by a nuclear genome, causes the reproductive barrier while the ...
TAKAHATA, Naoyuki, 尚之, 高畑
core   +1 more source

CYTOPLASMIC INCOMPATIBILITY IN POPULATIONS WITH OVERLAPPING GENERATIONS [PDF]

open access: yesEvolution, 2010
Many insects and other arthropods harbor maternally inherited bacteria inducing "cytoplasmic incompatibility" (CI), reduced egg hatch when infected males mate with uninfected females. CI-causing infections produce a frequency-dependent reproductive advantage for infected females.
openaire   +2 more sources

UNIDIRECTIONAL CYTOPLASMIC INCOMPATIBILITY IN THE MOSQUITO,AEDES ALBOPICTUS [PDF]

open access: yesEvolution, 1993
Endosymbiont-modulated cytoplasmic incompatibility (CI) is known to occur in several genera of insects includingAedes (Beckett et al., 1978; Trpis et al., 1981), Culex (Barr, 1982; Subbarao, 1982), Drosophila (Hoffmann et al., 1986; Hoffmann and Turelli, 1988; O'Neill and Karr, 1990), Laodelphax (Noda, 1984), Hypera (Hsiao and Hsiao, 1985), Nasonia ...
Srinivas, Kambhampati   +2 more
openaire   +2 more sources

Parasitism and maintenance of diversity in a fungal vegetative incompatibility system: the role of selection by deleterious cytoplasmic elements [PDF]

open access: yes, 2011
International audienceIn fungi, horizontal transmission of deleterious cytoplasmic elements is reduced by the vegetative incompatibility system. This self/non-self recognition system may select for greater diversity of fungal incompatibility phenotypes ...
Brusini, Jérémie   +8 more
core   +1 more source

Cytoplasmic incompatibility (CI) between Wolbachia infected and wild type mosquitoes. [PDF]

open access: yes, 2016
Cytoplasmic incompatibility (CI) between Wolbachia infected and wild type mosquitoes.
Jyotika Taneja De Bruyne (2150929)   +9 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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