ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Facilitating Wolbachia introductions into mosquito populations through insecticide-resistance selection. [PDF]
Wolbachia infections are being introduced into mosquito vectors of human diseases following the discovery that they can block transmission of disease agents.
Hoffmann, Ary A, Turelli, Michael
core +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
From parasite to mutualist: rapid evolution of Wolbachia in natural populations of Drosophila. [PDF]
Wolbachia are maternally inherited bacteria that commonly spread through host populations by causing cytoplasmic incompatibility, often expressed as reduced egg hatch when uninfected females mate with infected males.
Andrew R Weeks +4 more
doaj +1 more source
Acaricide resistance and genetic affinities of some selected populations of Tetranychus urticae Koch in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science (Horticultural) in Entomology at Massey University [PDF]
A study of resistance to acaricides in a number of populations of the two-spotted spider mite, Tetranychus urticae, in New Zealand had been carried out.
Ong, S. H.
core
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Demographic Variation of Wolbachia Infection in the Endangered Mitchell’s Satyr Butterfly
The Mitchell’s satyr, Neonympha mitchellii, is an endangered species that is limited to highly isolated habitats in the northern and southern United States.
Jennifer Fenner +7 more
doaj +1 more source
Symbiosis As The Way Of Eukaryotic Life: The Dependent Co-Origination Of The Body [PDF]
Molecular analyses of symbiotic relationships are challenging our biological definitions of individuality and supplanting them with a new notion of normal part whole relationships. This new notion is that of a \u27holobiont\u27, a consortium of organisms
Gilbert, Scott F.
core +2 more sources
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Transcriptional regulation of Culex pipiens mosquitoes by Wolbachia influences cytoplasmic incompatibility. [PDF]
Cytoplasmic incompatibility (CI) induced by the endosymbiont Wolbachia pipientis causes complex patterns of crossing sterility between populations of the Culex pipiens group of mosquitoes. The molecular basis of the phenotype is yet to be defined.
Sofia B Pinto +7 more
doaj +1 more source

