Results 51 to 60 of about 22,744 (213)

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

Med Research, EarlyView.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu, Aihetaimujiang Anwaier, Qintao Ge, Siqi Zhou, Xi Tian, Shuxuan Zhu, Guohai Shi, Yu Zhu, Dingwei Ye, Mierxiati Abudurexiti, Hailiang Zhang   +10 more
wiley   +1 more source

A Case of Erythroderma Secondary to Hypereosinophilia [PDF]

Journal of Clinical and Diagnostic Research, 2016
Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause.
Mohammed Shafi Abdulsalam, Hari Chandana Ghanta, Prabu Pandurangan, Maya Menon, Sheba S.K. Jacob   +4 more
doaj   +1 more source

CA-125 sebagai Prediktor Sitoreduksi pada Pasien Kanker Ovarium Tipe Epitel

Obgynia, 2023
Tujuan: Penelitian ini bertujuan untuk mengetahui apakah CA-125 dapat menjadi prediktor yang baik untuk sitoreduksi pada kanker ovarium tipe epitel. Metode: Desain penelitian ini adalah cross sectional dengan pemeriksaan pasien yang diduga memiliki ...
Bagja Dumas Darwizar, Gatot Nyarumenteng Adipurnawan Winarno, Jusuf Sulaeman Effendi   +2 more
doaj   +1 more source

Treatment of pediatric epilepsy

Pediatric Investigation, EarlyView.
Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li, Tinghong Liu, Chang Liu, Jie Deng, Shijie Wu, Suhui Kuang, Xiaotong Li, Zhirong Wei, Shuli Liang   +8 more
wiley   +1 more source

Peritoneal carcinomatosis [PDF]

, 2013
Several gastrointestinal and gynecological malignancies have the potential to disseminate and grow in the peritoneal cavity. The occurrence of peritoneal carcinomatosis (PC) has been shown to significantly decrease overall survival in patients with liver
Ansaloni L, BAIOCCHI, Gian Luca, Catena F., Coccolini F, Ghermandi C, GHEZA, Federico, GIULINI, Stefano Maria, Iusco D, Lotti M, Melotti R, Virzì S   +10 more
core   +1 more source

Comparison of ultrasound with computed tomography and whole‐body diffusion‐weighted MRI in prediction of surgical outcome using ESMO‐ESGO criteria in patients with tubo‐ovarian carcinoma: prospective ISAAC study

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To test the non‐inferiority of extended abdominopelvic ultrasound examination compared with contrast‐enhanced computed tomography (CT) and whole‐body diffusion‐weighted magnetic resonance imaging (WB‐DWI/MRI) in discriminating preoperatively between resectable and non‐resectable disease based on the European Society for Medical ...
D. Fischerova, P. Pinto, J. L. Alcázar Zambrano, J. Vara‐Garcia, V. Chiappa, F. Raspagliesi, D. Franchi, A. V. Urbinati, A. C. Testa, J. Jarkovsky, D. Cibula, F. Moro, Collaborators, F. Frühauf, J. Slama, R. Kocian, S. Alessi, G. Avesani, K. Benesova, A. Burgetova, G. Calareso, L. Lambert, M. Masek, A. Fagotti, C. Panico, P. Pricolo, R. Vigorito   +26 more
wiley   +1 more source

The next steps in improving the outcomes of advanced ovarian cancer [PDF]

, 2015
Worldwide ovarian cancer affects over 200,000 women per year. Overall survival rates are poor due to two predominate reasons. First, the majority of patients present with advanced disease creating significant difficulty with effecting disease eradication.
Blagden, S, Fotopoulou, C, Gabra, H, Openshaw, MR   +3 more
core   +1 more source

Polycythemia Vera and Essential Thrombocythemia: A Nationwide Population‐Based Study on Treatment Patterns, Vascular Complications and Survival

European Journal of Haematology, EarlyView.
ABSTRACT Background Polycythemia vera (PV) and essential thrombocythemia (ET) are associated with a well‐recognized increased risk of thrombotic events, bleeding, and all‐cause mortality, but the frequency of these outcomes during treatment has rarely been assessed in large cohorts.
Anneli Enblom Larsson, Henrik Renlund, Björn Andréasson, Henrik Holmberg, Maria Liljeholm, Anders Själander   +5 more
wiley   +1 more source

Diagnosing Systemic Mastocytosis: State of the Art

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley   +1 more source

Intraperitoneal chemotherapy for gastric cancer with peritoneal carcinomatosis: is HIPEC the only answer? [PDF]

, 2014
Gastric cancer with peritoneal carcinomatosis is notorious for its dismal prognosis. While the pathophysiology of peritoneal dissemination is still controversial, the rapid downhill course is universal.
Kwong, DLW, Lam, KO, Law, BTT, Law, SYK
core   +1 more source