Results 61 to 70 of about 17,628 (210)

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

Photochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore, Brian Schnoor, Kathryn L. McNaughton, Idrisa Rahman, Benjamin D. Powers, Dana M. Roque, Huang‐Chiao Huang   +6 more
wiley   +1 more source

Decreased turnover aspirin resistance by bidaily aspirin intake and efficient cytoreduction in myeloproliferative neoplasms

, 2018
Essential thrombocythemia (ET) and polycythemia vera (PV) are myeloproliferative neoplasms (MPN) with an increased risk of arterial and venous thrombosis.
Hubert Galinat, Andréas Perrier-Cornet, Jean-Christophe Ianotto, Eric Lippert, Maëla Perrot, Fanny Mingant   +5 more
core   +1 more source

Secondary surgical cytoreduction needs to be assessed taking into account surgical technique, completeness of cytoreduction, and extent of disease.

, 2020
Recent evidence suggested that secondary surgical cytoreduction followed by chemotherapy does not result in longer overall survival in patients with platinum-sensitive recurrent ovarian cancer.This statement is based on a phase III multicenter ...
Cascales-Campos, Pedro, Segura-Sampedro, Juan Jose, Arjona-Sanchez, Alvaro, Morales-Soriano, Rafael   +3 more
core   +1 more source

Stage IV Ovarian Cancer Is Not Uniformly Lethal: Two Subgroups With Stage II‐Like Outcomes Identified in Large Retrospective Cohorts

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background The International Federation of Gynecology and Obstetrics (FIGO) staging system for advanced ovarian cancer has remained largely static since 2014, with stage IV subdivided into IVA and IVB without further stratification. Emerging evidence suggests substantial prognostic heterogeneity within stage IV, yet large‐scale validation ...
Cheng Fang, Jundong Li, Qiaqia Li
wiley   +1 more source

Surgical Removal of Residual Tumor Masses in Patients Undergoing Targeted Therapy for EGFR‐Mutated Locally Advanced or Metastatic Lung Cancer

International Journal of Cancer, Volume 159, Issue 9, Page 2244-2261, 1 November 2026.
Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko, Daniil Stroyakovskiy, Evgeniy Levchenko, Mikhail Fedyanin, Albina Gabina, Ani Oganesian, Sergey Belukhin, Maria Stepanova, Ekaterina Stepanova, Elizaveta Artemyeva, Alexander Myslik, Nikita Volkov, Alexei Bogdanov, Tatiana Shuginova, Kirill Kryukov, Valeria Kheinshtein, Arif Allakhverdiev, Ivan Zaberegniy, Yana Akhmadiyarova, Mikhail Popov, Anastasiya Danilova, Dmitriy Sehniaidze, Nikita Savelov, Nikita Levchenko, Evgeniy Slugin, Olga Lopushanskaya, Ekaterina Kuligina, Svetlana Aleksakhina, Aglaya Iyevleva, Alexandr Ivantsov, Vladimir Moiseyenko, Evgeny Imyanitov   +31 more
wiley   +1 more source

Secondary cytoreduction plus oxaliplatin-based HIPEC in platinum-sensitive recurrent ovarian cancer patients: a pilot study

, 2009
To assess feasibility, complications and efficacy of secondary surgical cytoreduction (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in a selected group of platinum-sensitive recurrent ovarian cancer ...
A. Fagotti, A. Naldini, Grimolizzi, Filomena, Scambia, Giovanni, G. Vizzielli, I. Paris, Fagotti, Anna, Paris, Ida, F. Grimolizzi, G. Scambia, Fanfani, F, F. Fanfani, Paris I., Scambia G., Scambia, G., Fagotti A., Vizzielli, G., FANFANI, Francesco, Grimolizzi, F., Grimolizzi F., Naldini, A., Fagotti, A., Naldini A., Paris, I., Vizzielli G., Fanfani F.   +25 more
core   +1 more source

Recurrence Patterns After Complete Cytoreduction for Advanced Ovarian Cancer: Robotic Versus Open Surgery

Current Oncology
Background: Complete cytoreduction remains the primary surgical objective in advanced ovarian cancer and concerns persist that robotic surgery may result in distinct recurrence patterns and worse oncologic outcomes due to technical limitations, such as ...
Yossi Tzur, Yoav Brezinov, Tomer Bar-Noy, Amber Yasmeen, Melica Nourmoussavi Brodeur, Shannon Salvador, Walter H. Gotlieb, Susie Lau   +7 more
doaj   +1 more source

Estimating Individualized Survival Benefit of Consolidative Metastasis‐Directed Radiotherapy Following Chemoimmunotherapy in Nasopharyngeal Carcinoma With Exclusive Distant Metastasis

MedComm, Volume 7, Issue 11, November 2026.
This study integrates target trial emulation and causal machine learning to individualize consolidative metastasis‐directed radiotherapy (MDRT) for exclusively distant metastatic nasopharyngeal carcinoma. Using a multicenter cohort of 1083 patients, we confirmed overall MDRT efficacy via a cloning–censoring–weighting approach.
Xuguang Wang, Shuwei Chen, Xing Zhang, Linfei Mao, Jingtao Chen, Shida Yan, Jiawei Xie, Xianlu Gao, Liji Zheng, Yujie Zeng, Shiting Zhang, Zekun Deng, Mingyuan Du, Ming Song   +13 more
wiley   +1 more source

Rare Feline Gingival Extramedullary Plasmacytoma: Clinical Application of Electrochemotherapy for Local Control

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
This case report describes an aggressive gingival extramedullary plasmacytoma (EMP) with regional lymph node metastasis in a 14‐year‐old cat. As complete surgical excision was unfeasible, three weekly electrochemotherapy (ECT) sessions using intravenous bleomycin were performed for local tumour control.
Seulgi Hwang, Hayoung Ryu, Dong‐In Jung, DoHyeon Yu, Kyu‐Woan Cho, Hyeona Bae   +5 more
wiley   +1 more source

Is Optimal Cytoreduction Post Neoadjuvant Chemotherapy the Only Prognostic Factor in Advanced Ovarian Cancer?

, 2022
Background  Epithelial ovarian cancer (EOC) is one of the leading causes of cancer-related death in women. Approximately 70% of patients with EOC are diagnosed in advanced stage [The International Federation of Gynecology and Obstetrics(FIGO stage III ...
Dhiman, Pravesh, Raghupathi, Renu, Patil, C.N., P.P. Bapsy, Renu Raghupathi, Bapsy, P.P., Pravesh Dhiman, C.N. Patil   +7 more
core   +1 more source