Results 71 to 80 of about 17,628 (210)

Feasibility of a Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Program for Gastrointestinal and Gynecological Cancer Care in Newfoundland and Labrador

Onco
Peritoneal carcinomatosis is a common presentation found in advanced-stage gastrointestinal (GI) and gynecological cancers. Combined cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with significant survival
Kala Hickey, Stephanie Gill, Zoë Breen, Kaitlyn Harding, Hannah Yaremko, Alex Mathieson, Patti Power, David Pace, Joannie Neveu   +8 more
doaj   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, Volume 183, Issue 21, Page 6261-6290, November 2026.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Venetoclax as a cytoreduction therapy option for acute promyelocytic leukemia in newly diagnosed adult patients: a case report of a 35-year-old female with schizophrenia

Frontiers in Oncology
Venetoclax is effective in treating relapsed acute promyelocytic leukemia (APL), newly diagnosed pediatric APL, variant APL, and APL with central nervous system involvement. In newly diagnosed adult APL, venetoclax is rarely used.
Lingling Wang, Yuqing Miao, Yuexin Cheng
doaj   +1 more source

Splenectomy during secondary cytoreduction for ovarian cancer disease recurrence: Surgical and survival data

, 2006
Ovarian cancer disease recurs predominantly in the abdomen, with the spleen usually involved as part of a vast spread of upper-abdominal disease or, less frequently, as an isolated site of disease recurrence.
Natalina Manci, Roberto Angioli, Milena Pernice, BENEDETTI PANICI, PIERLUIGI, CALCAGNO, MARCO, MUZII, LUDOVICO, PERNICE, MILENA, Ludovico Muzii, Filippo Bellati, Marco Calcagno, BELLATI, FILIPPO, Sagit Arbel Alon, Pierluigi Bendetti Panici   +12 more
core   +1 more source

THE VALUE OF CYTOREDUCTIVE SURGERY FOR ISOLATED LYMPH NODE RECURRENCE OF OVARIAN CANCER

Сибирский онкологический журнал, 2020
The purpose of the study was to undertake a systematic literature review regarding the role of cytoreductive surgery in treatment of recurrent ovarian cancer, as well as to summarize available data on various current studies and estimate indications for ...
H. I. Mamajonov, S. O. Nikoghosyan, A. S. Shevchuk   +2 more
doaj   +1 more source

Molecular Mechanisms and Therapeutic Advances in KRAS G12C‐Mutant Non‐Small Cell Lung Cancer: Toward Mechanism‐Guided Longitudinal Management

Cancer Innovation, Volume 5, Issue 5, October 2026.
This review summarizes the molecular mechanisms, clinical development, resistance patterns, and emerging treatment strategies of KRAS G12C‐mutated non‐small cell lung cancer, with emphasis on approved inhibitors, combination approaches, next‐generation agents, and future directions from both global and Chinese perspectives.
Haiying Wang, Hanxiao Chen, Sheng Li, Jun Zhao   +3 more
wiley   +1 more source

TREATMENT OF SQUAMOUS CELL CARCINOMA OF THE SKIN WITH THE USE OG CRYOGENIC TECHNOLOGIES

Сибирский онкологический журнал, 2020
Background. The incidence of skin cancer has been steadily increasing worldwide. Squamous cell skin carcinoma (SCSC ) is the second most common form of epithelial cancer.
O. I. Baykalova, A. M. Belyaev, G. G. Prokhorov, Z. A.-G. Radzhabova   +3 more
doaj   +1 more source

Cytoreductive therapy reduces JAK2V617F+ blood velocity and adhesion to activated endothelium

British Journal of Haematology, EarlyView.
Angelica DaSilva, Taimur Ul Islam, Swati Menon, Julia Nguyen, Paul Krenik, Conglin Ruan, Xianghua Luo, David K. Wood, Joan D. Beckman   +8 more
wiley   +1 more source

Primary Cytoreduction and Survival for Patients With Less-Common Epithelial Ovarian Cancer [PDF]

This cohort study examines the association between primary cytoreduction status and survival for patients with less-common, advanced-stage epithelial ovarian ...
Matsuo, Koji, Roman, Lynda D., Gershenson, David M., Wright, Jason D, Wright, Jason D., Klar, Maximilian, Sood, Anil K., Gershenson, David M, Sood, Anil K, Roman, Lynda D, Chen, Ling   +10 more
core   +1 more source

Extreme Levels of Platelet Count in Essential Thrombocythemia: Management and Outcome, Report of Two Cases

Case Reports in Oncology, 2020
Myeloproliferative neoplasms including essential thrombocythemia (ET) is usually caused by somatic mutations in multiple genes, including the JAK2 (most frequently), CALR gene, and MPL. In rare cases, the disease is caused by other mutations such as THPO
Mohammad Abu-Tineh, Mohamed A. Yassin
doaj   +1 more source