Results 41 to 50 of about 37,531 (314)

Treatment options for PNET liver metastases. a systematic review [PDF]

, 2018
Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo, Crovetto, Anna, Debs, Tarek, Mangogna, Livia Maria, Moschetta, Giovanni, Nigri, Giuseppe, Persechino, Raffaello, Petrucciani, Niccolò, Ramacciato, Giovanni   +8 more
core   +1 more source

Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer [PDF]

, 2019
Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics ...
Ceelen, Wim, De Clercq, Kaat, De Wever, Olivier, Descamps, Benedicte, Hoorens, Anne, Vermeulen, An, Vervaet, Chris, Xie, Feifan   +7 more
core   +2 more sources

Intraperitoneal photodynamic therapy causes a capillary-leak syndrome. [PDF]

, 2003
BackgroundIn patients undergoing intraperitoneal (IP) photodynamic therapy (PDT), the combination of aggressive surgical debulking and light therapy causes an apparent systemic capillary-leak syndrome that necessitates significant intensive care unit ...
Canter, Robert J, Fraker, Douglas L, Glatstein, Eli J, Hahn, Stephen M, Kesmodel, Susan B, Metz, James M, Mick, Rosemarie, Raz, Dan J, Spitz, Francis R   +8 more
core   +2 more sources

The Delphi and GRADE methodology used in the PSOGI 2018 consensus statement on Pseudomyxoma Peritonei and Peritoneal Mesothelioma

, 2021
Pseudomyxoma Peritonei (PMP) and Peritoneal Mesothelioma (PM) are both rare peritoneal malignancies. Currently, affected patients may be treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy offering long-term survival or even ...
de Hingh, I.,, Deraco, M.,, Glehen, O.,, Govaerts, K.,, Kepenekian, V.,, Kusamura, S.,, Lund University., Lurvink, R.J,, Moran, B.,, PSOGI, Syk, Ingvar,, Van der Speeten, K.,, Villeneuve, L.,   +12 more
core   +1 more source

The acceleration of metastases after tumor removal and the paradoxical phenomenon of concomitant tumor resistance [PDF]

, 2018
Although surgical extirpation of tumors is usually clinically recommended, tumor removal may entail an undesired side effect: the risk of accelerating the growth of metastases.
Chiarella, Paula, Meiss, Roberto P., Montagna, Daniela Romina, Ruggiero, Raul Alejandro   +3 more
core   +1 more source

Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis : mission possible? [PDF]

, 2017
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Ceelen, Wim, Dakwar, George, De Smedt, Stefaan, Remaut, Katrien, Shariati, Molood, Willaert, Wouter   +5 more
core   +2 more sources

The current role of secondary cytoreductive surgery for recurrent ovarian cancer

Frontiers in Oncology, 2022
Ovarian cancer represents worldwide the second most frequent and the most fatal gynecological malignancy, with approximately two thirds of the patients presenting with advanced disease. Cytoreductive surgery, primary or after neoadjuvant chemotherapy, in
Eelco de Bree, Dimosthenis Michelakis, Elisavet Anagnostopoulou   +2 more
doaj   +1 more source

Peritoneal carcinomatosis from gastric cancer: a multi-institutional study of 159 patients treated by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy [PDF]

, 2010
BACKGROUND: Peritoneal carcinomatosis (PC) from gastric cancer has long been regarded a terminal disease with a short median survival. New locoregional therapeutic approaches combining cytoreductive surgery with perioperative intraperitoneal chemotherapy
Association Française de Chirurgie (AFC), B. Mansvelt, C. Arvieux, D. Elias, E. Cotte, F. Boutitie, F. Quenet, F.Noel Gilly, G. Lorimier, J.Marc Bereder, O. Glehen   +10 more
core   +2 more sources

The role of cytoreductive surgery in multifocal/multicentric glioblastoma

Brain and Spine, 2022
Abstract Purpose Multifocal/multicentric glioblastomas (mGBM) account for up to 20% of all newly diagnosed glioblastomas. The present study investigates the impact of cytoreductive surgery on survival and functional outcomes in patients with mGBM.
D. Dimov, D. Brainman, B. Berger, R. Coras, A. Grote, M. Simon   +5 more
openaire   +3 more sources

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

Advanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin, Jianyi Ding, Jie Liu, Haoran Hu, Yashi Zhu, Meiqin Yang, Huijuan Zhou, Baoyou Huang, Tiefeng Huang, Mengjie Li, Yinyan He, Ang Li, Lingfei Han   +12 more
wiley   +1 more source