Results 51 to 60 of about 2,605,313 (261)

The next steps in improving the outcomes of advanced ovarian cancer [PDF]

, 2015
Worldwide ovarian cancer affects over 200,000 women per year. Overall survival rates are poor due to two predominate reasons. First, the majority of patients present with advanced disease creating significant difficulty with effecting disease eradication.
Blagden, S, Fotopoulou, C, Gabra, H, Openshaw, MR   +3 more
core   +1 more source

Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer With Peritoneal Metastases (CYTO-CHIP study): A Propensity Score Analysis.

Journal of Clinical Oncology, 2019
PURPOSE Gastric cancer (GC) with peritoneal metastases (PMs) is a poor prognostic evolution. Cytoreductive surgery (CRS) yields promising results, but the impact of hyperthermic intraperitoneal chemotherapy (HIPEC) remains controversial. Here we aimed to
P. Bonnot, G. Piessen, V. Képénékian, E. Decullier, M. Pocard, B. Meunier, J. Bereder, K. Abboud, F. Marchal, F. Quénet, D. Goéré, S. Msika, C. Arvieux, N. Pirró, R. Wernert, P. Rat, J. Gagnière, J. Lefèvre, T. Courvoisier, R. Kianmanesh, D. Vaudoyer, M. Rivoire, P. Meeus, G. Passot, O. Glehen   +24 more
semanticscholar   +1 more source

Indications for hyperthermic intraperitoneal chemotherapy with cytoreductive surgery: a clinical practice guideline.

Current Oncology, 2020
Objective The purpose of the present review was to provide evidence-based guidance about the provision of cytoreductive surgery (crs) with hyperthermic intraperitoneal chemotherapy (hipec) in the treatment of peritoneal cancers.
R. Auer, D. Sivajohanathan, J. Biagi, J. Conner, E. Kennedy, T. May   +5 more
semanticscholar   +1 more source

Peritoneal carcinosis of ovarian origin [PDF]

, 2010
Epithelial ovarian cancer (EOC) is the second most common genital malignancy in women and is the most lethal gynecological malignancy, with an estimated five-year survival rate of 39%.
Fagotti, A, Fanfani, F, Gallotta, V, Naldini, A, ROMANO, Federico, Rossitto, C, Scambia, G., Vigliotta, M   +7 more
core   +2 more sources

Remote results of treatment of patients with advanced ovarian cancer after interval and delayed cytoreductive surgery: a retrospective single-center study

Опухоли женской репродуктивной системы
Background. Neoadjuvant chemotherapy is an option for the treatment of advanced ovarian cancer. The data about optimal chemotherapy cycles before surgery is contradictory.
P. I. Sorokin, D. O. Utkin, M. V. Novozhilov, Z. T. Abduragimova, S. E. Kulikova   +4 more
doaj   +1 more source

Clinical value of bioelectrical properties of cancerous tissue in advanced epithelial ovarian cancer patients [PDF]

, 2018
Currently, there are no valid pre-operatively established biomarkers or algorithms that can accurately predict surgical and clinical outcome for patients with advanced epithelial ovarian cancer (EOC).
Boutelle, Martyn G., Cunnea, Paula, Curry, Ed, Domenici, Lavinia, Drakakis, Emmanuel M., Fotopoulou, Christina, Gabra, Hani, Gorgy, Tommy, Gowers, Sally A. N., Lawton, Phillip, Leng Leong, Chi, Lu, Haonan, Morera, Cristina, Nixon, Katherine, Paterson, Andrew, Petkos, Konstantinos, Sorbi, Flavia, Wu, Wen   +17 more
core   +2 more sources

Prognostic factors influencing survival in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for isolated colorectal peritoneal metastases: a systematic review and meta‐analysis

Colorectal Disease, 2020
Peritoneal metastases from colorectal cancer confer the worst survival among all metastatic sites. The adoption of cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) can offer selected patients with isolated colorectal ...
V. Narasimhan, Sabrina Tan, Joseph C. H. Kong, T. Pham, M. Michael, R. Ramsay, S. Warrier, A. Heriot   +7 more
semanticscholar   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Immune checkpoint inhibitors plus debulking surgery for patients with metastatic renal cell carcinoma: clinical outcomes and immunological correlates of a prospective pilot trial

Nature Communications
Surgical removal of primary tumors reverses tumor-mediated immune suppression in pre-clinical models with metastatic disease. However, how cytoreductive surgery in the metastatic setting modulates the immune responses in patients, especially in the ...
Sangeeta Goswami, Jianjun Gao, Sreyashi Basu, Daniel D. Shapiro, Jose A. Karam, Rebecca Slack Tidwell, Kamran Ahrar, Matthew T. Campbell, Yu Shen, Alexandro E. Trevino, Aaron T. Mayer, Alexsandra B. Espejo, Christian Seua, Marc D. Macaluso, Yulong Chen, Wenbin Liu, Zhong He, Shalini S. Yadav, Ying Wang, Priya Rao, Li Zhao, Jianhua Zhang, Sonali Jindal, Nizar M. Tannir, Andrew Futreal, Linghua Wang, Padmanee Sharma   +26 more
doaj   +1 more source

Cytoreductive Surgery and Peritonectomy Procedures [PDF]

Indian Journal of Surgical Oncology, 2016
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has become widely accepted as an effective method of treating peritoneal metastases (PM) from various cancers. CRS performed with the goal of removing all the macroscopic disease and comprises of peritonectomy procedures and visceral resections.
Sanket S, Mehta, Aditi, Bhatt, Olivier, Glehen   +2 more
openaire   +2 more sources