Results 51 to 60 of about 2,521,326 (308)

Neoadjuvant chemotherapy followed by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal cancer: a feasibility and safety study

World Journal of Surgical Oncology, 2019
Background Standard treatment for colorectal peritoneal carcinomatosis typically involves cytoreductive surgery, hyperthermic intraperitoneal chemotherapy (HIPEC), and if possible, postoperative adjuvant chemotherapy. However, a substantial percentage of
M. Leimkühler, P. H. J. Hemmer, A. K. L. Reyners, D. J. A. de Groot, R. J. van Ginkel, L. B. Been, G. H. de Bock, B. L. van Leeuwen   +7 more
doaj   +1 more source

All exceptional surgeries on alternating knots are integral surgeries [PDF]

Algebr. Geom. Topol. 8 (2008) 2161-2173, 2008
We show that all exceptional surgeries on hyperbolic alternating knots in the 3-sphere are integral surgeries.
arxiv   +1 more source

Clinical value of bioelectrical properties of cancerous tissue in advanced epithelial ovarian cancer patients [PDF]

, 2018
Currently, there are no valid pre-operatively established biomarkers or algorithms that can accurately predict surgical and clinical outcome for patients with advanced epithelial ovarian cancer (EOC).
Boutelle, Martyn G., Cunnea, Paula, Curry, Ed, Domenici, Lavinia, Drakakis, Emmanuel M., Fotopoulou, Christina, Gabra, Hani, Gorgy, Tommy, Gowers, Sally A. N., Lawton, Phillip, Leng Leong, Chi, Lu, Haonan, Morera, Cristina, Nixon, Katherine, Paterson, Andrew, Petkos, Konstantinos, Sorbi, Flavia, Wu, Wen   +17 more
core   +2 more sources

On mapping cones of Seifert fibered surgeries [PDF]

J. Topol. 5 (2012), no. 2, 366-376, 2011
Using the mapping cone of a rational surgery, we give several obstructions for Seifert fibered surgeries, including obstructions on the Alexander polynomial, the knot Floer homology, the surgery coefficient and the Seifert and four-ball genus of the knot.
arxiv   +1 more source

Positive Surgical Margins in the 10 Most Common Solid Cancers. [PDF]

, 2018
A positive surgical margin (PSM) following cancer resection oftentimes necessitates adjuvant treatments and carries significant financial and prognostic implications.
Califano, Joseph A, Clary, Bryan, Cohen, Ezra EW, Kane, Christopher, Lippman, Scott M, Messer, Karen, Molinolo, Alfredo, Murphy, James D, Nguyen, Quyen T, Orosco, Ryan K, Pang, John, Sacco, Assuntina, Tapia, Viridiana J, Tringale, Kathryn R, Wallace, Anne   +14 more
core   +2 more sources

The Peritoneal Cancer Index is a Strong Predictor of Incomplete Cytoreductive Surgery in Ovarian Cancer

Annals of Surgical Oncology, 2020
Background Extent of tumor load is an important factor in the selection of ovarian cancer patients for cytoreductive surgery (CRS). The Peritoneal Cancer Index (PCI) gives exact information on tumor load but still is not standard in ovarian cancer ...
B. Jónsdóttir, M. Lomnytska, I. Poromaa, I. Silins, K. Stålberg   +4 more
semanticscholar   +1 more source

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model [PDF]

, 2015
Cytoreductive surgery combined with intraperitoneal chemotherapy (IPC) is currently the standard treatment for selected patients with peritoneal carcinomatosis of colorectal cancer.
Ceelen, Wim, De Wever, Olivier, Descamps, Benedicte, Gremonprez, Félix, Izmer, Andrei, Vanhaecke, Frank, Vanhove, Christian   +6 more
core   +4 more sources

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena, Ceelen, Wim, Remaut, Katrien, Van Ramshorst, Gabrielle, Willaert, Wouter   +4 more
core   +1 more source

ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: A comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas [PDF]

, 2013
<b>Objective</b> <i>ABCB1</i> encodes the multi-drug efflux pump P-glycoprotein (P-gp) and has been implicated in multi-drug resistance.
, Bean, Yukie, Beckmann, Matthias W., Beesley, Jonathan, Berchuck, Andrew, Brown, Robert, Camey, Michael E., Chen, Xiaoqing, Chenevix-Trench, Georgia, Cramer, Daniel W., Cunningham, Julie M, deFazio, Anna, Despierre, Evelyn, du Bois, Andreas, Ekici, Arif B., Emmanuel, Catherine, Fasching, Peter A., Fereday, Sian, Fridley, Brooke L., Gao, Bo, Goode, Ellen L., Goodman, Marc T., Haber, Michelle, Harter, Philipp, Hedditch, Ellen L., Heitz, Florian, Henderson, Michelle J., Hogdall, Claus, Hogdall, Estrid, Jensen, Allan, Johnatty, Sharon E., Karlan, Beth Y., Kjaer, Susanne K., Lambrechts, Sandrina, Law, Matthew H., Lester, Jenny, Levine, Douglas A., Lu, Yi, Lurie, Galina, MacGregor, Stuart, Norris, Murray D., Paul, Jim, Pejovic, Tanja, Russell, Amanda J., Schwaab, Ira, Shildkraut, Joellen, Terry, Kathryn L., Thompson, Pamela J., Vergote, Ignace, Vierkant, Robert A., Webb, Penelope M.   +50 more
core   +1 more source

Efficacy of Surgical Treatment of Peritoneal Carcinomatosis in Patients with Colorectal Cancer

Galician Medical Journal, 2016
Colorectal cancer is one of the most common types of cancer in Ukraine. Prognosis for patients with peritoneal carcinomatosis is unfavorable, and life expectancy is typically less than 6 months.
T G Fetsych, A P Revura
doaj   +1 more source