Results 131 to 140 of about 52,861 (267)
Identification of direct targets and modified bases of RNA cytosine methyltransferases
Nature Biotechnology, 2013 The extent and biological impact of RNA cytosine methylation are poorly understood, in part owing to limitations of current techniques for determining the targets of RNA methyltransferases. Here we describe 5-azacytidine–mediated RNA immunoprecipitation (
Vahid Khoddami, B. Cairns
semanticscholar +1 more source
RESEARCHES ON PYRIMIDINES: SYNTHESIS OF CYTOSINE-5-ACETIC ACID. [FIFTY-FIRST PAPER.]1 [PDF]
, 1911 Treat B. Johnson +2 more
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Adsorption of cytosine and aza derivatives of cytidine on Au single crystal surfaces [PDF]
arXiv, 2013 The adsorption of cytosine on the Au(111) and Au(110) surfaces has been studied using both aqueous deposition and evaporation in vacuum to prepare the samples. Soft X-ray photoelectron spectroscopy (XPS) and near edge X-ray absorption fine structure spectroscopy (NEXAFS) were used to determine the electronic structure and orientation of the adsorbates.
arxiv
Angewandte Chemie International Edition, Accepted Article.Chemical probes that control the function of complex RNA molecules offer unique opportunities to interrogate biological systems. In this study, we demonstrate that a small molecule ligand selectively recognizes and undergoes traceless, reversible photocrosslinking to PreQ1 RNA aptamers.
Shaifaly Parmar +5 more
wiley +1 more source
Chirality Induced Spin Selectivity – the Photoelectron View
Israel Journal of Chemistry, Volume 62, Issue 11-12, December 2022., 2022 Abstract In this short overview we discuss the manifestation of the chirality‐induced spin selectivity (CISS) effect in photoelectron spectroscopy experiments with direct spin analysis. Various systems, from the initially investigated monolayers of molecular biosystems and organic hepta‐helicene to recent chirally grown solid oxide films, are evaluated.
Paul V. Möllers +2 more
wiley +1 more source
Nature CommunicationsThe engineered TadA variants used in cytosine base editors (CBEs) present distinctive advantages, including a smaller size and fewer off-target effects compared to cytosine base editors that rely on natural deaminases.
Guoling Li +17 more
doaj +1 more source
Effects of cytosine methylation on transcription factor binding sites
BMC Genomics, 2014 DNA methylation in promoters is closely linked to downstream gene repression. However, whether DNA methylation is a cause or a consequence of gene repression remains an open question.
Y. Medvedeva +9 more
semanticscholar +1 more source
AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis
Nature Communications, 2018 In diffuse large B-cell lymphoma (DLBCL) increased epigenetic heterogeneity in the form of cytosine methylation is known to link to a poor clinical outcome.
Matt Teater +14 more
doaj +1 more source
Next Generation Epigenetic Detection Technique:Identifying Methylated DNA using Graphene Nanopore [PDF]
arXiv, 2014 DNA methylation plays a pivotal role in the genetic evolution of both embryonic and adult cells. For adult somatic cells, location and dynamics of methylation has been very precisely pinned down with the 5-cytosine markers on cytosinephosphate- guanine (CpG) units.
arxiv
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome
Genome Research, 2014 Epigenetic information is available from contemporary organisms, but is difficult to track back in evolutionary time. Here, we show that genome-wide epigenetic information can be gathered directly from next-generation sequence reads of DNA isolated from ...
J. S. Pedersen +20 more
semanticscholar +1 more source