Results 181 to 190 of about 52,861 (267)

Advances in Isotope Labeling for Solution Nucleic Acid NMR Spectroscopy

open access: yesChemPlusChem, Accepted Article.
The availability of nucleic acid structural biology methods still lags behind that of proteins, as evidenced by the significantly smaller number of structures deposited in the PDB. The highly skewed ratio of nucleic acid structures, relative to their protein counterparts (~1:50), is inverted with respect to the cellular output of RNA and proteins in ...
Stefan Hilber   +3 more
wiley   +1 more source

Relative importance of genotype, gene expression, and DNA methylation on complex traits in perennial ryegrass

open access: yesThe Plant Genome, Volume 15, Issue 4, December 2022., 2022
Abstract The growing demand for food and feed crops in the world because of growing population and more extreme weather events requires high‐yielding and resilient crops. Many agriculturally important traits are polygenic, controlled by multiple regulatory layers, and with a strong interaction with the environment.
Marta Malinowska   +12 more
wiley   +1 more source

DNA‐Cytosine methylation in E. coli MRE 600 cells [PDF]

open access: bronze, 1976
Irina Bogdarina   +2 more
openalex   +1 more source

Skeletal Muscle Memory: An Update From the Antidoping Perspective

open access: yesDrug Testing and Analysis, EarlyView.
ABSTRACT This narrative review explores the concept of muscle memory, focusing on the physiological and biochemical mechanisms underlying information retention in skeletal muscle tissue as it relates to antidoping. The discussion encompasses the role of satellite cells (SCs) in myonuclei recruitment, resulting in increased myonuclear density and ...
Claire Traversa
wiley   +1 more source

CRISPR applications for Duchenne muscular dystrophy: From animal models to potential therapies

open access: yesWIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023
CRISPR‐Cas9 gene‐editing technology enables the rapid generation of animal models for Duchenne muscular dystrophy research and has potential to be developed as CRISPR therapy for the long lasting genetic correction of causal mutations. Abstract CRISPR gene‐editing technology creates precise and permanent modifications to DNA.
Yu C. J. Chey   +4 more
wiley   +1 more source

THE EFFECTS OF CYTOSINE ARABINOSIDE ON CANINE RENAL ALLOGRAFTS

open access: bronze, 1969
Joseph L. Alexander   +3 more
openalex   +1 more source

Cytosine methylation and the ecology of intragenomic parasites.

open access: yesTrends in Genetics, 1997
J. Yoder, C. Walsh, T. Bestor
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

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