Results 191 to 200 of about 133,095 (262)

Cytosine methylation contributes to the fitness of <i>Caulobacter</i> cells naturally expressing a Vsr-like protein. [PDF]

iScience
Matthey N, Wennubst G, Pellaton N, Bojkowska K, Marquis J, Collier J.   +5 more
europepmc   +1 more source

YBX1 Promotes Malignant Progression of HNSCC via Stabilizing NSUN2‐m5C Modified ATF4 mRNA

Cancer Science, EarlyView.
The diagram depicts the core axis and the key finding: “Targeting YBX1/NSUN2 abrogates HNSCC progression”. Within left‐sided HNSCC cells, NSUN2 mediates m5C methylation on the CDS of ATF4 mRNA; YBX1 then specifically recognizes and binds this modified site, augmenting ATF4 mRNA stability, which ultimately promotes cancer cell proliferation, migration ...
Yanwei Li, Shuang Li, Yang Li, Zhanyu Pan   +3 more
wiley   +1 more source

A Cytosine Deaminase-Based Genomic Footprinting Assay (cFOOT-seq) for Detecting Transcription Factor Occupancy. [PDF]

Bio Protoc
Yang MC, Wu A, Wang H, Liu X, Shi J, Gao S, Zhang JM.   +6 more
europepmc   +1 more source

Ionizing Radiation and Ultraviolet Light Irradiation‐Associated DNA Damage Increasing Genomic Instability Risk

Cancer Science, EarlyView.
UV irradiation induces two major types of pyrimidine dimers, CPDs and 6–4PPs. Whereas 6–4PPs efficiently induce cell‐cycle arrest, CPDs do not and frequently persist into S phase. As a result, DSBs can arise in the presence of unrepaired CPDs after 6–4PPs have been repaired, increasing the risk of genomic instability.
Ken‐ichi Yoshioka, Yusuke Matsuno, Rika Kusumoto‐Matsuo   +2 more
wiley   +1 more source

Whole genome sequence analysis of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> KL101 and comparative genomics with BB12. [PDF]

J Anim Sci Technol
Kim K, Lee J, Kang SJ, Oh S.
europepmc   +1 more source

A bacterial defense system targeting modified cytosine of phage genomic DNA. [PDF]

Nat Commun
Liu R, Tang D, Niu M, Lei S, Zong Z, Chen Q, Yu Y.   +6 more
europepmc   +1 more source

A pentose, as a cytosine nucleobase modification in <i>Shewanella</i> phage Thanatos genomic DNA, mediates enhanced resistance toward host restriction systems. [PDF]

Appl Environ Microbiol
Brandt D, Dörrich AK, Persicke M, Kemmler A, Leonhard T, Haak M, Nölting S, Ruwe M, Schmid N, Thormann KM, Kalinowski J.   +10 more
europepmc   +1 more source

Epigenetic insights into food allergy: The potential role of DNA methylation in diagnosis and management. [PDF]

World Allergy Organ J
Kim SL, Beadell AV, Ciaccio CE.
europepmc   +1 more source

Unnatural Cytosine Analogs Potentiate a Customizable, Enzymatic Method for Integrated Epigenetic and Four-Base Genetic Sequencing. [PDF]

J Am Chem Soc
Loo CE, Parker JB, Barka A, Zhu R, Schnell MR, Cuomo RG, Zhu H, Liu L, Chen A, Gill J, Zhou W, Kohli RM.   +11 more
europepmc   +1 more source

Loss of DNA methylation is not associated with venetoclax–hypomethylating agents synergy in acute myeloid leukaemia cells

British Journal of Haematology, EarlyView.
Aida Selimović‐Pašić, Lisa Haglund, Maike Bensberg, Júlia Goldmann, Padraig D'arcy, Sandra Hellberg, Colm E. Nestor   +6 more
wiley   +1 more source