Results 181 to 190 of about 160,622 (298)

A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin. [PDF]

Chemistry
You Y, Suen MC, Miao H, Geng Y, Din RU, Yuan M, Xue Q, Li X, Xu N, Guo Z, Lam HM, Lo KW, Liu C, Zhu G.   +13 more
europepmc   +1 more source

Ionizing Radiation and Ultraviolet Light Irradiation‐Associated DNA Damage Increasing Genomic Instability Risk

Cancer Science, EarlyView.
UV irradiation induces two major types of pyrimidine dimers, CPDs and 6–4PPs. Whereas 6–4PPs efficiently induce cell‐cycle arrest, CPDs do not and frequently persist into S phase. As a result, DSBs can arise in the presence of unrepaired CPDs after 6–4PPs have been repaired, increasing the risk of genomic instability.
Ken‐ichi Yoshioka, Yusuke Matsuno, Rika Kusumoto‐Matsuo   +2 more
wiley   +1 more source

Genetic and Epigenetic Diversity of <i>Salmonella enterica</i> Isolates from Clinical and Veterinary Sources in Kazakhstan. [PDF]

Pathogens
Yessimseit DT, Rysbekova AK, Zhumadilova ZB, Abdeliyev BZ, Tukhanova NB, Kassenova AK, Abdrakhmanova AK, Mereke A, Agzam SD, Nurpeisova AS, Nissanova R, Maksatova AM, Reva ON, Abdirassilova AA.   +13 more
europepmc   +1 more source

Genetic Engineering of Tumor‐Infiltrating Lymphocytes (TIL) via a T‐Editor Platform to Enhance Anti‐Tumor Activity

Cancer Science, EarlyView.
A rapid and efficient CRISPR‐mediated gene editing platform for TIL engineering identified FAM84B as a novel potential target to enhance antitumor activity and pioneered the use of CBE to generate FAM84B loss‐of‐function TIL with enhanced antitumor activity.
Fenge Li, Xuejiao Ma, Yongming Xue, Jilong Yang, Ruijing Wang, Xiang Li, Chao Zhang, Wenhan Lu, Mei Liu, Yue Xu, Xinyi Wang, Shengnan Wu, Ning Kang, Chunhua Ma   +13 more
wiley   +1 more source

Characterization of Regioisomeric Conjugates Arising from Pixantrone at AP Sites in DNA. [PDF]

Biochemistry
Fu Y, Terrell JT, Kellum A, Pallan PS, Galindo-Murillo R, Rizzo CJ, Egli M, Stone MP.   +7 more
europepmc   +1 more source

Tryptase Locus Variation Contributes to Normal‐Range Basal Serum Tryptase Variability and Is Associated With Anaphylaxis

Clinical &Experimental Allergy, EarlyView.
Tryptase locus variation explains normal‐range baseline serum tryptase differences and is associated with Hymenoptera venom anaphylaxis, independent of clonal mast cell disease and HαT. ABSTRACT Background Increased basal serum tryptase level (BST) is associated with anaphylaxis.
Manca Svetina, Jonathan J. Lyons, Peter Kopač, Julij Šelb, Mitja Košnik, Matija Rijavec, Peter Korošec   +6 more
wiley   +1 more source

m5C Methylation of mRNA: Still More Questions Than Answers. [PDF]

Cells
Babaylova ES, Zolotenkova EA, Malygin AA.   +2 more
europepmc   +1 more source

Clues of ancient incomplete lineage sorting during bivalve evolution undermine support for Heterodonta

Cladistics, EarlyView.
Abstract A long‐standing challenge in phylogenomics has been the resolution of relationships originated from ancient radiations. In these cases, phenomena such as incomplete lineage sorting can increase the support for conflicting resolutions. Most of the diversity in the Class Bivalvia originated during an Ordovician radiation; indeed, several deep ...
Alessandro Formaggioni, Takeshi Takeuchi, Mayuko Hamada, Kazuhiro Saito, Tatsuya Sakamoto, Noriyuki Satoh, Federico Plazzi, Marco Passamonti   +7 more
wiley   +1 more source

Case Report: Two cases of secondary malignant neoplasms following treatment in pediatric patients. [PDF]

Front Pediatr
Wang Y, Zhang H, Miao Q, Li L, Xu F, Mao X, Jiang X.   +6 more
europepmc   +1 more source