Results 211 to 220 of about 52,861 (267)

Remission maintenance for acute nonlymphocytic leukemia cytosine arabinoside plus 6-thioguanine versus a sequence of drug regimens [PDF]

open access: bronze, 1980
Gary A. Presant   +3 more
openalex   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Sedimentary ancient DNA from caves: Challenges and opportunities

open access: yesJournal of Quaternary Science, EarlyView.
Abstract Caves are unique depositional environments that hold great potential for long‐term preservation of DNA due to their typically cool and stable internal climates, buffered from external climate extremes. Bones from caves have long been recognised as an excellent source of ancient DNA, yet the potential for DNA preservation in cave sediments ...
Siobhan Evans   +2 more
wiley   +1 more source

Purification of Cytosine Deaminase from Pseudomonas aureofaciens

open access: bronze, 1975
Takuo Sakai   +3 more
openalex   +1 more source

Molecular Classification of Endometrial Cancers Using an Integrative DNA Sequencing Panel

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Adoption of molecular classification in endometrial cancer (EC) into clinical practice remains challenging due to complexity in coordination of multiple assays. We aimed to develop a simple molecular technique to classify ECs into four subgroups using our custom‐designed targeted sequencing panel.
Soyoun R. Kim   +13 more
wiley   +1 more source

Exploration of Neurodegenerative Diseases Using Long‐Read Sequencing and Optical Genome Mapping Technologies

open access: yesMovement Disorders, EarlyView.
Abstract Genetic factors play a central role in neurodegenerative disorders. Over the past few decades, significant progress has been made in identifying the causative genes of numerous monogenic disorders, largely due to the widespread adoption of next‐generation sequencing (NGS) technologies in both research and clinical settings.
Guillaume Cogan   +4 more
wiley   +1 more source

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