Results 281 to 290 of about 279,378 (380)

Studies on the Relationship between Therapeutic Schedule and Antitumor Effect of Etoposide and Cytosine Arabinoside in Murine L1210 Leukemia

, 1989
Kazuya Ooi, Toshiki Ohkubo, Hajime Kawasaki, Minoru Sakurai   +3 more
openalex   +2 more sources

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Modification of cytosine moieties of nucleic acids with hydrogen sulfide (nucleosides and nucleotides. XXXIV).

, 1980
Kazunobu Miura, Tohru Ueda
openalex   +2 more sources

Understanding of endo/lysosomal escape of nanomaterials in biomedical application

Smart Molecules, EarlyView.
This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang, Haoyu Li, Chen Chen, Zhihui Liang   +3 more
wiley   +1 more source

Synergistic optimization enhancing the precision and efficiency of cytosine base editors in poplar. [PDF]

Commun Biol
Liu H, Zhang M, Sun L, Peng Y, Sun Y, Fan Y, Li H, Liu D, Lu H.   +8 more
europepmc   +1 more source

Molecular structure of (m⁵dC-dG)³: the role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA

, 1982
Satoshi Fujii, Andrew H.‐J. Wang, Gijs van der Marel, Jacques H. van Boom, Alexander Rich   +4 more
openalex   +2 more sources

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Epigenetic landscape of hormone-independent sexual dimorphism and characterization of canine XIST. [PDF]

Sci Rep
Oh SJ, Kang D, Jang S, Kim TS, Hong CY, Choe YH, Jo CH, You AS, Do YJ, Rho GJ, Kim J, Lee SL.   +11 more
europepmc   +1 more source

Design, Mechanisms, and Applications of DNA‐Mediated Dynamically Reconfigurable Plasmonic Gold Nanostructures

Small Methods, EarlyView.
This review provides key principles of designing and synthesizing reconfigurable plasmonic gold nanostructures for generating and controlling physical, chemical, and biological properties and functions. The recent advances in the biological and materials applications of dynamically reconfigurable plasmonic gold nanostructures are also summarized ...
So Young Choi, Jieun Kim, Eun Ho Song, Eunhye Park, Jingrui Wu, Juyeon Yoo, Jwa‐Min Nam   +6 more
wiley   +1 more source