Results 51 to 60 of about 279,378 (380)
Effectiveness of the enzyme cytosine deaminase in the free living ciliary organism Tetrahymena pyriformis (Ehrenberg, 1830) [PDF]
Cytosine deaminase (EC.3.5.4.1) activity and properties was determined in the extract of the free living ciliata Tetrahymena pyriformis grown in proteose peptone medium. The optimum conditions for the enzyme activity was also determined and it was found
Zahraa Bashi, Muna Jankeer
doaj +1 more source
Consecutive Silver(I) Ion Incorporation into Oligonucleotides containing Cytosine‐Cytosine Mispairs [PDF]
AbstractInvited for this month's cover is the group of Prof. Heinz‐Bernhard Kraatz from the University of Toronto, Canada. The cover picture shows the consecutive incorporation of AgI ions into a DNA duplex containing adjacent C−C mispairs. Read the full text of the article at 10.1002/cplu.202000607.
M. Nur Hossain+2 more
openaire +3 more sources
Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis [PDF]
Background\ud DNA methylation is an epigenetic mechanism associated with regulation of gene expression and it is modulated during chemical carcinogenesis.
Chipman, J Kevin+4 more
core +4 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Aim: Lung cancer is considered to be the most common cancer in the world. In humans, about 50% or more cancers have a mutated tumor suppressor p53 gene thereby resulting in accumulation of p53 protein and losing its function to activate the target genes ...
Rashid Mir+9 more
doaj +1 more source
Shotgun metagenomic sequencing is a powerful approach to study microbiomes in an unbiased manner and of increasing relevance for identifying novel enzymatic functions.
Weiwei Yang+9 more
doaj +1 more source
An EPR study on cytosine irradiated
AbstractIn this study, paramagnetic centers over the cytosine were formed by photolysis then these centers were investigated using EPR method. EPR signals were not recorded from non‐irradiated the cytosine, but irradiated polycrystalline exhibited complex EPR spectra. For obtaining of cytosine polycrystalline, novel crystallization method was performed
Usta, Ayhan+5 more
openaire +8 more sources
Cytosine-Based TET Enzyme Inhibitors.
DNA methylation is known as the prima donna epigenetic mark for its critical role in regulating local gene transcription. Changes in the landscape of DNA methylation across the genome occur during cellular transition, such as differentiation and altered ...
Gabriella N. L. Chua+9 more
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Diversity of cytosine methylation across the fungal tree of life
The generation of thousands of fungal genomes is leading to a better understanding of genes and genomic organization within the kingdom. However, the epigenome, which includes DNA and chromatin modifications, remains poorly investigated in fungi.
A. Bewick+7 more
semanticscholar +1 more source