Results 71 to 80 of about 52,861 (267)
Nature Communications, 2016 Cytosine mutations within TCA/T motifs are common in cancer. A likely cause is the DNA cytosine deaminase APOBEC3B (A3B). However, A3B-null breast tumours still have this mutational bias.
G. Starrett +11 more
semanticscholar +1 more source
Advanced Materials Interfaces, EarlyView.The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur +3 more
wiley +1 more source
An Unusual 500,000 Bases Long Oscillation of Guanine and Cytosine Content in Human Chromosome 21 [PDF]
Computational Biology and Chemistry, 28(5-6): 393-399 (2004), 2004 An oscillation with a period of around 500 kb in guanine and cytosine content (GC%) is observed in the DNA sequence of human chromosome 21. This oscillation is localized in the rightmost one-eighth region of the chromosome, from 43.5 Mb to 46.5 Mb. Five cycles of oscillation are observed in this region with six GC-rich peaks and five GC-poor valleys ...
arxiv +1 more source
Nature Communications, 2018 Circadian rhythmicity governs a remarkable array of fundamental biological functions and is mediated by cyclical transcriptomic and proteomic activities. Epigenetic factors are also involved in this circadian machinery; however, despite extensive efforts,
Gabriel Oh +15 more
semanticscholar +1 more source
Exploring DNA Functionalization Techniques for Silver Nanoparticles
Advanced Materials Interfaces, EarlyView.This study evaluates four functionalization methods—salt‐aging, pH‐assisted, freezing‐directed, and microwave‐assisted—for attaching DNA strands to 20 nm silver nanoparticles (AgNPs). The resulting DNA‐AgNP conjugates are characterized and colloidal stability and DNA loading are assessed.
Sebastian Freko +3 more
wiley +1 more source
Genetic variations in the human cannabinoid receptor gene are associated with happiness.
PLoS ONE, 2014 Happiness has been viewed as a temporary emotional state (e.g., pleasure) and a relatively stable state of being happy (subjective happiness level).
Masahiro Matsunaga +6 more
doaj +1 more source
Universal 1/f noise, cross-overs of scaling exponents, and chromosome specific patterns of GC content in DNA sequences of the human genome [PDF]
Physical Review E, 71, 041910 (2005), 2004 Spatial fluctuations of guanine and cytosine base content (GC%) are studied by spectral analysis for the complete set of human genomic DNA sequences. We find that (i) the 1/f^alpha decay is universally observed in the power spectra of all twenty-four chromosomes, and that (ii) the exponent alpha \approx 1 extends to about 10^7 bases, one order of ...
arxiv +1 more source
Recurrent acquisition of cytosine methyltransferases into eukaryotic retrotransposons
Nature Communications, 2018 Transposable elements are in a constant arms race with the silencing mechanisms of their host genomes. One silencing mechanism commonly used by many eukaryotes is dependent on cytosine methylation, a covalent modification of DNA deposited by C5 cytosine ...
Alex de Mendoza +14 more
semanticscholar +1 more source
Frequency‐Dependent Demethylation of Cancer DNAs by High‐Power Terahertz Radiation
Advanced Photonics Research, EarlyView.Effective demethylation of cancer DNA is successfully demonstrated by resonant irradiation with high‐power terahertz (THz) waves at the 10 mW level, combined with metamaterial‐based THz filters. The dependence of spectral filtering on demethylation indicates that the resonant frequency of 1.6 THz of cancer DNAs plays a crucial role in reducing the ...
Chaeyoon Kim +8 more
wiley +1 more source
Cytosine Methylation: Quantitation by Automated Genomic Sequencing and GENESCANTM Analysis
BioTechniques, 1996 Bisulfite treatment and PCR amplification of genomic DNA permits the methylation analysis of any cytosine residue in a target sequence. By cloning and sequencing the PCR product, the methylation of individual molecules can be determined, whereas direct ...
Cheryl L. Paul, Susan J. Clark
doaj +1 more source