Results 131 to 140 of about 560,464 (384)

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

open access: yesArthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla   +13 more
wiley   +1 more source

Quantifying single‐platelet biomechanics: An outsider’s guide to biophysical methods and recent advances

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Platelets are the key cellular components of blood primarily contributing to formation of stable hemostatic plugs at the site of vascular injury, thus preventing excessive blood loss.
Laura Sachs   +3 more
doaj   +1 more source

Orchestrating mitochondria in neurons: Cytoskeleton as the conductor

open access: yesCytoskeleton, 2019
Mitochondria are crucial to support synaptic activity, particularly through ATP production and Ca2+ homeostasis. This implies that mitochondria need to be well distributed throughout the different neuronal sub‐compartments.
Carlos Cardanho-Ramos   +2 more
semanticscholar   +1 more source

Lung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome

open access: yesAdvanced Biology, EarlyView.
This study aims to evaluate the efficacy of primed mesenchymal stem cells (pMSCs) as an alternative treatment for Acute Respiratory Distress Syndrome (ARDS), based on a novel lung microphysiological system (MPS) to test the efficacy of pMSCs over the standard treatment, Dexamethasone.
Bokyong Kim   +11 more
wiley   +1 more source

Osteocytes under Mechanical Loading Regulate PC‐3 Cancer Cell–Mineral Interactions during Early‐Stage Metastasis to Bone

open access: yesAdvanced Biology, EarlyView.
In this study, Seaman et al. develop a co‐culture assay to examine interactions between prostate cancer cells and mineralized osteoblasts in a microfluidic platform. The authors collect conditioned media from static or flow‐stimulated osteocytes and demonstrate that mechanical loading of osteocytes regulates the growth of prostate cancer cells and ...
Kimberly Seaman   +5 more
wiley   +1 more source

The cytoskeleton in phagocytosis and macropinocytosis

open access: yesCurrent Biology, 2021
S. Mylvaganam, S. Freeman, S. Grinstein
semanticscholar   +1 more source

Osteogenic Effects of Ion Released from Biodegradable Metallic Magnesium and Calcium Coating

open access: yesAdvanced Biology, EarlyView.
This study explores how magnesium–calcium coatings on titanium promote osteogenesis by releasing ions and elevating pH during degradation. Using osteoblast‐like cells, the research demonstrates that both ion release and pH changes contribute to cell proliferation, differentiation, and mineralization, offering new insights into the design of bioactive ...
Risa Miyake   +4 more
wiley   +1 more source

SUN/KASH interactions facilitate force transmission across the nuclear envelope. [PDF]

open access: yes, 2019
LINC complexes (Linker of Nucleoskeleton and Cytoskeleton), consisting of inner nuclear membrane SUN (Sad1, UNC-84) proteins and outer nuclear membrane KASH (Klarsicht, ANC-1, and Syne Homology) proteins, are essential for nuclear positioning, cell ...
Hao, Hongyan, Starr, Daniel A
core  

Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton

open access: yesJournal of Cell Biology, 2016
Fungal and human septins can distinguish between different degrees of micron-scale curvature in cells, suggesting that this property of the septin cytoskeleton provides a cell with a mechanism to sense its local shape.
Andrew A. Bridges   +4 more
semanticscholar   +1 more source

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