Results 111 to 120 of about 484,240 (263)

NPFs-mediated actin cytoskeleton: a new viewpoint on autophagy regulation

Cell Communication and Signaling
Macroautophagy/autophagy is a lysosome-dependent catabolic process induced by various cellular stress conditions, maintaining the homeostasis of cells, tissues and organs.
Yuan Dong, Chengshi Quan
doaj   +1 more source

Amoeboid cells undergo durotaxis with soft end polarized NMIIA

eLife
Cell migration towards stiff substrates has been coined as durotaxis and implicated in development, wound healing, and cancer, where complex interplays between immune and non-immune cells are present.
Chenlu Kang, Pengcheng Chen, Xin Yi, Dong Li, Yiping Hu, Yihong Yang, Huaqing Cai, Bo Li, Congying Wu   +8 more
doaj   +1 more source

Cofilin: a missing link between T cell co-stimulation and rearrangement of the actin cytoskeleton [PDF]

, 2000
Kyeong‐Hee Lee, Stefan Meuer, Yvonne Samstag   +2 more
openalex   +1 more source

Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis

Nature Communications
The extracellular matrix (ECM) controls tumour dissemination. We characterise ECM organization in human and mouse tumours, identifying three regions: tumour body, proximal invasive front and distal invasive front.
Oscar Maiques, Marta C. Sallan, Roman Laddach, Pahini Pandya, Adrian Varela, Eva Crosas-Molist, Jaume Barcelo, Olivia Courbot, Yanbo Liu, Vittoria Graziani, Youssef Arafat, Joanne Sewell, Irene Rodriguez-Hernandez, Bruce Fanshawe, Yaiza Jung-Garcia, Paul RC Imbert, Eloise M. Grasset, Jean Albrengues, Maria Santacana, Anna Macià, Jordi Tarragona, Xavier Matias-Guiu, Rosa M. Marti, Sophia Tsoka, Cedric Gaggioli, Jose L. Orgaz, Gilbert O. Fruhwirth, Fredrik Wallberg, Kai Betteridge, Constantino Carlos Reyes-Aldasoro, Syed Haider, Andrejs Braun, Sophia N. Karagiannis, Alberto Elosegui-Artola, Victoria Sanz-Moreno   +34 more
doaj   +1 more source

MAP2 phosphorylation: mechanisms, functional consequences, and emerging insights

Frontiers in Cellular Neuroscience
Microtubule-associated protein 2 (MAP2) is a key regulator of cytoskeletal dynamics and neuronal function. It stabilizes microtubules, shapes dendrites, influences synaptic plasticity, and regulates transportation and protein synthesis through its ...
Jiali Lyu, Jiali Lyu, Andrew G. DeMarco, Robert A. Sweet, Robert A. Sweet, Robert A. Sweet, Melanie J. Grubisha, Melanie J. Grubisha   +7 more
doaj   +1 more source

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity [PDF]

, 1994
The myristoylated form of c-Abl protein, as well as the P210bcr/abl protein, have been shown by indirect immunofluorescence to associate with F-actin stress fibers in fibroblasts. Analysis of deletion mutants of c-Abl stably expressed in fibroblasts maps
Baltimore, David, Jackson, Peter K., Janmey, Paul A., Matsudaira, Paul T., Sanders, Mitchell C., Van Etten, Richard A.   +5 more
core   +4 more sources

Detergent-resistant cytoskeleton of the surface-activated platelet differs from the suspension-activated platelet cytoskeleton [PDF]

, 1992
Smith Cm, SM Burris, G. H. Rao, J G White   +3 more
openalex   +1 more source

The polar code for patterning: how polarity and the cytoskeleton orchestrate asymmetric cell division during plant development

Frontiers in Cell and Developmental Biology
Cell polarity is fundamental to morphogenesis across living organisms. In plants, a dynamic interplay between polarity cues and the cytoskeleton orchestrates essential asymmetric cell divisions across diverse species.
Akanksha Garhewal, Gabriel J. Angres, Andrew Muroyama   +2 more
doaj   +1 more source

INFLUENZA A VIRUS (IAV) MAY INDUCE CYTOSKELETON DYSFUNCTION IN POLYMORPHONUCLEAR LEUKOCYTES (PMNL) BY DEPRESSING PROTEIN PHOSPHORYLATION [PDF]

, 1987
J. Gary Wheeler, L F Cassidy, Susan E Caldwell, David Bass, Jon S. Abramson   +4 more
openalex   +1 more source

Kinetic regulation of kinesin’s two motor domains coordinates its stepping along microtubules

eLife
The two identical motor domains (heads) of dimeric kinesin-1 move in a hand-over-hand process along a microtubule, coordinating their ATPase cycles such that each ATP hydrolysis is tightly coupled to a step and enabling the motor to take many steps ...
Yamato Niitani, Kohei Matsuzaki, Erik Jonsson, Ronald D Vale, Michio Tomishige   +4 more
doaj   +1 more source