Results 131 to 140 of about 343,555 (313)
Advanced Materials, EarlyView.A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee +9 more
wiley +1 more source
Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells
Advanced Materials, EarlyView.The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz +5 more
wiley +1 more source
Advanced Materials, EarlyView.We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena +7 more
wiley +1 more source
The dynamic status of actin in the regulation of environmental sensing and homeostatic control in Saccharomyces cerevisiae [PDF]
, 2014 Actin is a highly conserved protein in eukaryotes which forms dynamic cytoskeletal structures. Rapid remodeling of actin filaments is important for the regulation of a broad range of critical cellular processes.
Smethurst, Daniel George Jan
core
Advanced Materials, EarlyView.Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello +5 more
wiley +1 more source
Cytoskeleton-interacting proteins in brainstem development : roles of KCC2 and Vangl2
, 2010 The brainstem is the most evolutionary conserved division of the brain. It develops from the hindbrain and midbrain regions of the neural tube and forms neural networks that regulate vital functions of the body.
Zachi Horn (18652342)
core +1 more source
Nature CommunicationsThe extracellular matrix (ECM) controls tumour dissemination. We characterise ECM organization in human and mouse tumours, identifying three regions: tumour body, proximal invasive front and distal invasive front.
Oscar Maiques +34 more
doaj +1 more source
Cytochalasins as Modulators of Stem Cell Differentiation
CellsRegenerative medicine aims to identify new research strategies for the repair and restoration of tissues damaged by pathological or accidental events. Mesenchymal stem cells (MSCs) play a key role in regenerative medicine approaches due to their specific
Luca Pampanella +6 more
doaj +1 more source
, 2021 The spatiotemporal organisation of cells is essential for the correct performance of organisms, which implies a complex and highly regulated system. In eukaryotic cells, this aspect is of particular importance, with the cytoskeleton playing a key role as
Braga, Teresa
core
Advanced Materials, EarlyView.A microfluidic method is presented which enables parallelized fabrication of rod‐shaped microgels, based on step‐emulsification (SE) droplet generation and subsequent droplet distribution and confinement, combined in a single device. Microgel rods are fabricated in parallel at different flow rates based on two light‐mediated crosslinking chemistries ...
Matthias Mork +5 more
wiley +1 more source