Results 151 to 160 of about 560,464 (384)

Understanding the link between the actin cytoskeleton and prion biology

, 2023
Jane E. Dorweiler, Anita L. Manogaran
openalex   +2 more sources

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Cytochalasins as Modulators of Stem Cell Differentiation

Cells
Regenerative medicine aims to identify new research strategies for the repair and restoration of tissues damaged by pathological or accidental events. Mesenchymal stem cells (MSCs) play a key role in regenerative medicine approaches due to their specific
Luca Pampanella, Giovannamaria Petrocelli, Provvidenza Maria Abruzzo, Cinzia Zucchini, Silvia Canaider, Carlo Ventura, Federica Facchin   +6 more
doaj   +1 more source

Amplification of the Melanocortin-1 Receptor in Nephrotic Syndrome Identifies a Target for Podocyte Cytoskeleton Stabilization [PDF]

, 2018
Lovisa Bergwall, Hanna Wallentin, Johannes Elvin, Peidi Liu, Roberto Boi, Carina Sihlbom, Kyle Hayes, Dale Wright, Börje Haraldsson, Jenny Nyström, Lisa Buvall   +10 more
openalex   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Identification of molecular markers associated to new sources of resistance to the root-knot nematode in cotton : S02T04 [PDF]

, 2013
The root-knot nematode (RKN) Meloidogyne incognita is a major constraint in cotton (Gossypium hirsutum L.) production in numerous countries. Control of RKN has been hampered by the lack of options for crop rotation and even more, by the lack of high ...
Barroso, Paulo Augusto Vianna, Carneiro, Regina Maria Dechechi Gomes, Giband, Marc, Lacape, Jean-Marc, Moretzsohn, Márcio C.   +4 more
core  

Enhanced reaction kinetics in biological cells

, 2008
The cell cytoskeleton is a striking example of "active" medium driven out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to have a spectacular impact on the mechanical and rheological properties of the cellular medium, as well as
A Ajdari, B Alberts, C Storm, C. Loverdo, D Holcman, D Mizuno, F Nedelec, FJ Nedelec, G Kolesov, H Salman, I Eliazar, J Howard, K Kruse, L Le Goff, M Coppey, M Slutsky, M. Moreau, MA Lomholt, MF Shlesinger, MF Shlesinger, MP Sheetz, O Berg, O Bénichou, O Bénichou, O Bénichou, O Thoumine, O. Bénichou, P Dalhaimer, R Voituriez, R Voituriez, R. Voituriez, S Condamin, S Huet, S Redner   +33 more
core   +1 more source

Bacterial cell division is recognized by the septin cytoskeleton for restriction by autophagy [PDF]

, 2019
Sina Krokowski, Serge Mostowy
openalex   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source