Results 71 to 80 of about 307,661 (330)
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Identification of Actin Filament-Associated Proteins in Giardia lamblia
Microbiology Spectrum, 2021 The deep-branching protozoan parasite Giardia lamblia is the causative agent of the intestinal disease giardiasis. Consistent with its proposed evolutionary position, many pathways are minimalistic or divergent, including its actin cytoskeleton.
Melissa C. Steele-Ogus +3 more
doaj +1 more source
Stochastic Dynamics of Magnetosomes in Cytoskeleton
, 2004 Rotations of microscopic magnetic particles, magnetosomes, embedded into the cytoskeleton and subjected to the influence of an ac magnetic field and thermal noise are considered.
Benzi R. +10 more
core +1 more source
Cilium structure, assembly, and disassembly regulated by the cytoskeleton
Biochemical Journal, 2018 The cilium, once considered a vestigial structure, is a conserved, microtubule-based organelle critical for transducing extracellular chemical and mechanical signals that control cell polarity, differentiation, and proliferation.
Mary Mirvis, T. Stearns, W. James Nelson
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Frontiers in ImmunologyAggregation of high-affinity IgE receptors (FcϵRIs) on granulated mast cells triggers signaling pathways leading to a calcium response and release of inflammatory mediators from secretory granules.
Vadym Sulimenko +7 more
doaj +1 more source
eLife, 2021 Apoptosis is characterized by profound morphological changes, but their physiological purpose is unknown. To characterize the role of apoptotic cell contraction, ROCK1 was rendered caspase non-cleavable (ROCK1nc) by mutating aspartate 1113, which ...
Linda Julian +12 more
doaj +1 more source
The Role of the Microtubule Cytoskeleton in Neurodevelopmental Disorders
Frontiers in Cellular Neuroscience, 2018 Neurons depend on the highly dynamic microtubule (MT) cytoskeleton for many different processes during early embryonic development including cell division and migration, intracellular trafficking and signal transduction, as well as proper axon guidance ...
Micaela Lasser +2 more
semanticscholar +1 more source
The mammalian endocytic cytoskeleton
European Journal of Cell Biology, 2022 Clathrin-mediated endocytosis (CME) is the major route through which cells internalise various substances and recycle membrane components. Via the coordinated action of many proteins, the membrane bends and invaginates to form a vesicle that buds off-along with its contents-into the cell.
Abouelezz Amr, Almeida-Souza Leonardo
openaire +4 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source