Results 191 to 200 of about 322,139 (355)

PIM1 Attenuates Innate Immunity to Foster Coronavirus Replication through Ubiquitin Ligase β‐TrCP‐Mediated IFNAR1 Degradation

Advanced Science, EarlyView.
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan, Lin Zhu, Cien Chen, Li Zhong, Houying Leung, Wei Li, Chang Xu, Xi Yao, Huan Hu, Mandi Wu, Yuxin Hou, Hin Chu, Yiran Wang, Sheng Chen, Mingyu Pan, Zongwei Cai, Ming‐liang He   +16 more
wiley   +1 more source

Studying relative RNA localization from nucleus to the cytosol. [PDF]

NAR Genom Bioinform
Ntasis VF, Guigó R.
europepmc   +1 more source

Effects of Cytosol on Transcription in Isolated Simian-Virus-40-Infected Nuclei [PDF]

, 1979
Isaac Icekson, Moshé Yaniv
openalex   +1 more source

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

Advanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan, Dongxiao Cui, Jiajian Guo, Xiaojing Ma, Jiaming Wang, Linyue Guo, Tianyu Li, Mingrui Yang, Guangrui Huang, Anlong Xu, Wenfu Ma   +10 more
wiley   +1 more source

Stressful situations: Molecular insights on mitochondrial quality control pathways. [PDF]

J Biol Chem
Romanelli S, Trempe JF.
europepmc   +1 more source

Intrinsic membrane glycoproteins with cytosol-oriented sugars in the endoplasmic reticulum. [PDF]

, 1988
Claudia Abeijón, C B Hirschberg
openalex   +1 more source

NPR1 Modulates Cross-Talk between Salicylate- and Jasmonate-Dependent Defense Pathways through a Novel Function in the Cytosol Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.009159.

The Plant Cell Online, 2003
Steven H. Spoel, A. Koornneef, S.M.C. Claessens, J. Korzelius, Johan A Van Pelt, Martin J. Mueller, A. Buchala, J. Metraux, Rebecca L. Brown, K. Kazan, L. van Loon, Xinnian Dong, C. Pieterse   +12 more
semanticscholar   +1 more source

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

Advanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen, Xue‐Fei Tian, Teng Yang, Yu‐Jie Dai, Da‐Yuan Chen, Hong‐Bo Chen, Takaya Shimura, Xin‐Fang Li, Chu‐Lin Sha, Qing Ji, Jun Cao, Mei‐Yu Fang, Jin‐Biao Shang, Jian‐Min Fang, Ye Lu, Wei‐Hui Zheng, Peng Guo, Wei‐Hong Tan   +17 more
wiley   +1 more source

The global proteome of <i>Streptococcus pneumoniae</i> EF3030 under nutrient-defined <i>in vitro</i> conditions. [PDF]

Front Cell Infect Microbiol
De S, Busch LM, Burchhardt G, Gesell Salazar M, Schlüter R, Steil L, Völker U, Hammerschmidt S.   +7 more
europepmc   +1 more source

Ligandin retains and albumin loses bilirubin binding capacity in liver cytosol.

, 1978
Irving Listowsky, Zenaida Gatmaitan, Irwin M. Arias   +2 more
openalex   +1 more source