Results 211 to 220 of about 323,927 (286)

Translating Blue Light Stimulation From Batch to Perfusion: Process and Intracellular Metabolic Analysis

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Improving cell‐specific productivity remains a central objective in biopharmaceutical manufacturing. In this study, the effect of blue light illumination on IgG1‐producing CHO DP‐12 cells was systematically evaluated across batch, fed‐batch, and perfusion cultivations in controlled 3 L bioreactor systems.
Stefanie Föller, Attila Teleki, Ralf Takors   +2 more
wiley   +1 more source

Vagus nerve control of HMGB1 accessibility: a bioelectronic strategy for inflammation and pain. [PDF]

Bioelectron Med
Yang H, Brines M, Andersson U.
europepmc   +1 more source

Species Dynamics and Gene Expression in Algal Polycultures Under Mixotrophic Cultivation in Outdoor Pilot‐Scale Nordic Conditions

Biotechnology and Bioengineering, EarlyView.
These results demonstrate that mixotrophic conditions drive both microbial community shifts and metabolic reprogramming, underscoring the importance of cultivation strategy and polyculture selection for targeted applications such as nutrient recovery and bioproduct generation.
Quyen Nham, Hanna Farnelid, Catherine Legrand, Elin Lindehoff   +3 more
wiley   +1 more source

Carbon dioxide concentration alters cyanobacterial carboxysome encapsulation and redox state in Synechococcus sp. PCC 7002. [PDF]

Commun Biol
Huffine CA, Fontana CG, Garris RL, Sempeck C, Cameron JC, Avramov A.   +5 more
europepmc   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Host prenylation promotes membrane association of the <i>Salmonella</i> effector GtgE during infection. [PDF]

Microbiology (Reading)
Cattelan N, Yu H, Przybyszewska K, Solano-Collado V, Colamarino R, Baldassarre M, Spanò S.   +6 more
europepmc   +1 more source

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino, Christopher R. Friesen, Geoffrey E. Hill, Dalton C. Leibold, Pablo Recio, Karine Salin, Kristoffer H. Wild, Daniel W.A. Noble   +7 more
wiley   +1 more source

Organelle-centered resistosome signaling in plant immunity. [PDF]

Plant Commun
Wang Q, Yang Y, Zhang L, Chang M.
europepmc   +1 more source

Heat stress in spermatogenesis: a redox‐dependent decision network linking ROS, autophagy, and regulated cell death

Biological Reviews, EarlyView.
ABSTRACT Heat stress (HS) is an increasing threat to male reproductive health, disrupting spermatogenesis through complex and interdependent cellular responses within the seminiferous epithelium. Although excessive reactive oxygen species (ROS) production is a hallmark of HS, ROS also act as central regulators of cell fate decisions beyond their role ...
Ribrio Ivan Tavares Pereira Batista
wiley   +1 more source

Acetyl-CoA-dependent processes are preferentially supported by local metabolite synthesis. [PDF]

Sci Adv
Supplee JG, Costa-Pinheiro P, Wessendorf-Rodriguez K, Stransky S, Yang Q, Demetriadou C, Murali N, Li J, Pennise JL, Marcinkiewicz MM, Sidoli S, Snyder NW, Metallo CM, Marmorstein R, Wellen KE.   +14 more
europepmc   +1 more source