Results 231 to 240 of about 453,068 (302)

Sudden elevation of carbon dioxide concentration causes perturbation of the electron transport chain and triggers defense responses in Arabidopsis thaliana. [PDF]

Planta
Shokouhi D, Hernandez JS, Walther D, Kepp G, Schwenkert S, Leister D, Gremmels J, Zuther E, Alpers J, Nägele T, Heyer AG.   +10 more
europepmc   +1 more source

Correction for Waldeck-Weiermair et al., Dynamic regulation of receptor-modulated endothelial NADPH oxidases. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Mechanism-based inactivation of human aldehyde oxidase by erlotinib: Mechanistic insights from structural analogs and molecular docking. [PDF]

Mol Pharmacol
Kweh JR, Ng NKM, Ngoh LM, Li CJY, Tan BJ, Tan WK, Mettu VS, Austin-Muttitt K, Mullins JGL, Lau AJ.   +9 more
europepmc   +1 more source

Ciliary p75 neurotrophin receptor (p75NTR) facilitates the enrichment of exogenous amyloid beta (Aβ 1-42) peptide and promotes oxidative stress in human hippocampal astrocytes. [PDF]

BMC Mol Cell Biol
Gupta A, Thirugnanam K, Bice Z, Lowman AK, Rarick KR, LaViolette PS, Pan A, Franczak M, Ramchandran R.   +8 more
europepmc   +1 more source

Berberine alleviates pyroptosis of retinal ganglion cells in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Mitochondrial DNA: a molecular switch driving sterile neuroinflammation. [PDF]

Transl Neurodegener
Jauhari A, Singh T, Carlisle DL, Friedlander RM.   +3 more
europepmc   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

International Journal of Cancer, EarlyView.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn, Rachel Lawrence, Hasan Haboubi, Hamsa Naser, Kate Hurlow, Ume‐Kulsoom Shah, Lisa Williams, Sarah Gwynne, Owen Bodger, Jiri Zavadil, Francois Virard, Shareen Doak, Laura E. Thomas, Gareth Jenkins   +13 more
wiley   +1 more source

A generalizable assay for intracellular accumulation to profile cytosolic drug delivery in mammalian cells. [PDF]

Commun Chem
Bhandari S, Ongwae GM, Dash R, Liu Z, Chordia MD, He Y, Pires MM.   +6 more
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

A kinetic mathematical model of comprehensive iron metabolism in a respiring yeast cell: a basic-pathways approach to solving a large system dynamically. [PDF]

Biometals
Lindahl PA, Walton JR.
europepmc   +1 more source