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Background: Liver failure represents a life-threatening organ dysfunction with liver transplantation as the only proven curable therapy to date. Liver assist devices have been extensively researched to either bridge such patients to transplantation or ...
Mihai Popescu, Dana Tomescu
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Cytosorb® hemoadsorption of apixaban during emergent cardio-pulmonary bypass: a case report
Peri-operative coagulation management of patients receiving apixaban, a new oral anticoagulant, is difficult. The CytoSorb ® hemoadsorption device might represent a therapeutic option to reduce apixaban's pharmacological and inflammatory effects during ...
Vitor Mendes +2 more
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Successful Treatment of Severe Lamotrigine Intoxication with CytoSorb Hemoadsorption
Blood Purification, 2021Severe intoxication with the anti-epileptic drug, lamotrigine can cause cardiovascular collapse, neurotoxicity – expressed as intractable seizures, and even death. As there is currently no known specific antidote, extracorporeal removal therapies such as CytoSorb hemoadsorption might represent a promising therapeutic option.
Caterina, Reuchsel +1 more
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Use of CytoSorb in cases of acute amitriptyline intoxication
Journal of Clinical Pharmacy and Therapeutics, 2021Intoxications with the tricyclic antidepressant amitriptyline frequently occur in the clinical setting and require immediate treatment. Although various poisonings can be counteracted with specific remedies, treatment options for amitriptyline intoxication remain sparse.
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Novel use of Cytosorb™ haemadsorption to provide biochemical control in liver impairment
We describe the use of Cytosorb™, a synthetic extracorporeal haemoperfusion adsorption column, in the management of two patients with drug induced cholestasis and a third with alcoholic hepatitis and subsequent acute on chronic liver failure.
A Austin
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CytoSorb purification in critically ill SARS-CoV-2 patients
The International Journal of Artificial Organs, 2021Objective: To describe the experience with CytoSorb treatment in patients with refractory acute respiratory distress syndrome (ARDS) following SARS-CoV-2 infection. Methods: Retrospective observational study on 15 patients treated in a
Pieri M. +4 more
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Extracorporeal Blood Purification with CytoSorb in 359 Critically Ill Patients
Blood Purification, 2023Introduction: Critically ill patients with inflammatory dysregulation and organ disfunction may benefit from blood purification, although the use of this technique has not been described in large case series. We evaluated clinical outcomes and survival in high-risk intensive care unit (ICU) patients who underwent extracorporeal blood purification ...
Marina Pieri +7 more
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[Is the time ripe for cytosorb].
Deutsche medizinische Wochenschrift (1946), 2016Hemofiltration with Cytosorb can reduce cytokines in sepsis. Since cytokines are involved in the development of vasodilatatory shock in sepsis, their reduction might improve the chance of survival in this condition. In spite of the CE-approval of Cytosorb clinical efficacy has not been proved so far.
Markus, Gehling, Michael, Tryba
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Combined Use of CytoSorb and ECMO in Patients with Severe Pneumogenic Sepsis
The Thoracic and Cardiovascular Surgeon, 2020Abstract Background High morbidity and mortality are frequently reported in intensive care patients suffering from severe sepsis with systemic inflammation. With the development of severe respiratory failure, extracorporeal membrane oxygenation (ECMO) is often required.
Ali, Akil +6 more
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Successful Treatment of Severe Digitoxin Intoxication with CytoSorb® Hemoadsorption
Blood Purification, 2020While several intoxications can be successfully treated with specific antidotes, intoxications with the steroid glycoside digitoxin still represent a major challenge. Besides conventional approaches, CytoSorb<sup>®</sup> hemoadsorption might be another treatment option.
Thomas Georg Karl Breuer +4 more
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