Results 11 to 20 of about 871,555 (308)

Cytotoxic activity in cutaneous leishmaniasis [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 2017
Cutaneous leishmaniasis (CL) is a chronic disease caused by species of the protozoan Leishmania and characterised by the presence of ulcerated skin lesions. Both parasite and host factors affect the clinical presentation of the disease.
Taís M Campos   +3 more
doaj   +3 more sources

Cytotoxic Activity of Some Lupeol Derivatives [PDF]

open access: yesNatural Product Communications, 2016
The synthesis of 3- O -acyl derivatives of lupeol is presented, as well as lupenone and the oxime of lupenone. The obtained derivatives were subjected to the MTT test in order to evaluate their cytotoxic activity toward HeLa, KB, MCF-7 and A-549 cell ...
Barbara Bednarczyk-Cwynar   +2 more
doaj   +3 more sources

Chromatogram Profiles and Cytotoxic Activity of Irradiated Mahkota Dewa (Phaleria Macrocarpa Scheff. Boerl) Leaves [PDF]

open access: yesAtom Indonesia, 2011
Gamma irradiation has been used by the industries for preservation of herbal medicine, but it has not been studied the effect of gamma irradiation on their efficacy, especially their bioactivity as anticancer substances.
E. Katrin1, Selvie2, H. Winarno1
doaj   +1 more source

Synthesis and biological activity of novel zingerone-thiohydantoin hybrids [PDF]

open access: yesJournal of the Serbian Chemical Society, 2022
A series of zingerone–thiohydantoin hybrids were synthesized from O-alkyl zingerone derivatives by cyclocondensation with thiosemicarbazide in a two-step reaction. The obtained new potentially bioactive compounds were structurally characterized by IR and
Virijević Katarina D.   +6 more
doaj   +1 more source

Traditional varieties and wild pear from Serbia: a link among antioxidant, antidiabetic and cytotoxic activities of fruit peel and flesh [PDF]

open access: yesBotanica Serbica, 2021
This study was aimed at evaluating the antioxidant and antidiabetic activities of methanolic extracts of peel, flesh and mixed peel, and flesh, as well as the cytotoxic activity of mixed peel and flesh extracts obtained from fruits of six traditional ...
Mariana Oalđe Pavlović   +6 more
doaj   +1 more source

Cytotoxic Activity of Orsellinates [PDF]

open access: yesZeitschrift für Naturforschung C, 2006
Abstract The series of 2,4-dihydroxy-6-methylbenzoates 2-10 (methyl to hexyl orsellinates) prepared by alcoholysis of lecanoric acid (1) - a natural product from the lichen Parmotrema tinctorum (Nyl.) Hale - was submitted to the brine shrimp lethality test (BST), which was also performed for 2,4-dihydroxy-6-methylbenzoic acid (11 ...
Alcir T, Gomes   +4 more
openaire   +2 more sources

In vitro assessment of the cytotoxic effects of novel RGD analogues [PDF]

open access: yesBioDiscovery, 2012
The RGD sequence is present in many extracellular matrix proteins and intracellular proteins, including caspases. Synthetic RGD peptides may affect adhesion, migration and tumour metastasis, or directly induce apoptosis.
Anelia Balacheva   +5 more
doaj   +3 more sources

Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity

open access: yesChemistry Proceedings, 2021
Through the reaction of fullerenylazide with terminal acetylenes, previously undescribed 1-butyl-2-triazolylfullerenes, in which the heterocyclic fragment was directly attached to the fullerene backbone, were synthesized for the first time. Water-soluble
Zarema R. Sadretdinova   +5 more
doaj   +1 more source

(3-(1H-Indol-3-yl)-2-(7,8,12,13-tetraoxa-10-azaspiro[5.7]tridecan-10-yl)propanoic acid) with Cytotoxic Activity

open access: yesMolbank, 2023
An efficient method for the synthesis of 3-(1H-indol-3-yl)-2-(7,8,12,13-tetraoxa-10-azaspiro[5.7]tridecan-10-yl)propanoic acid) via condensation of 7,8,10,12,13-pentaoxaspiro[5.7]tridecane with tryptophan under the action of a catalyst based on Sm(NO3)3 ...
Nataliya N. Makhmudiyarova   +3 more
doaj   +1 more source

Chemical modifications of a natural xanthone and antimicrobial activity against multidrug resistant Staphylococcus aureus and cytotoxicity against human tumor cell lines

open access: yesQuímica Nova, 2011
A series of 15 ω-aminoalkoxylxanthones containing methyl, ethyl, propyl, tert-butylamino and piperidinyl moieties were synthesized from a natural xanthone isolated from a lichen species.
Ana Camila Micheletti   +9 more
doaj   +1 more source

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