Synthesis and Cytotoxic Activity of Some Novel Thieno[2,3-d:4,5-d']Dipyrimidine Derivatives
Synthesis of some novel tricyclic compounds bearing thienodipyrimidine moiety by the reaction of ethyl 6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,2-d]pyrimidine-7-carboxylate (1) with different types of aromatic amines to give the ...
Elsherbiny Hamdy El-Sayed +1 more
doaj +1 more source
Evaluation of bioactivities and phenolic composition of extracts of Salvia officinalis L. (Lamiaceae) collected in Montenegro [PDF]
Sage (Salvia officinalis) is the best-known species of the genus Salvia, due to its medicinal and flavouring properties. This research was conducted on samples of S. officinalis collected from Potoci (SOP) in the continental part of Montenegro and from
Sonja Duletić-Laušević +7 more
doaj +1 more source
Thiosemicarbazone analogs of papaveraldine and related compounds 1–6 were synthesized and evaluated for cytotoxic and antimalarial activities.
Somsak Ruchirawat +2 more
doaj +1 more source
CYTOTOXIC ACTIVITY OF COMBINED FIG EXTRACT AND OLIVE OIL AGAINST BREAST CANCER CELLS
Figs and olive oil are plants containing flavonoids compounds. Flavonoids have antioxidant and cytotoxic activities. This study aims to find out the antioxidant and cytotoxic activities of fig extract, olive oil and combination of fig and olive oil as ...
Naniek Widyaningrum +4 more
doaj +1 more source
Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines
Several 2-unsubstituted thieno[2,3-d]pyrimidines have been prepared from 2-aminothiophene-3-carboxylic acid esters and their carbonitrile analogs. Some triazolo-thienopyrimidine and 2-thioxothienopyrimidine representatives have also been synthesized ...
Khulud M. Al-Taisan +2 more
doaj +1 more source
Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic Factor [PDF]
WE have reported that cell contact per se is not sufficient to explain the rapid and dramatic in vitro destruction of target L cells observed when they are treated with immune lymphocytes or non-immune phytohaemagglutinin (PHA)-stimulated lymphocytes derived from various inbred mice1.
Granger, G A, Williams, T W
openaire +4 more sources
Cytotoxic Activity of Metal Nanoparticle Complexes
Metal complexes are widely used in pharmaceutics, cosmetics, electronics, casting printing and power generation. One of the major challenges due to their long-term use as medicines is their accumulation in the body.
Nidhi Singh +4 more
doaj +1 more source
Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses [PDF]
The immune response to HIV-1 in patients who carry human histocompatibility leukocyte antigen (HLA)-B27 is characterized by an immunodominant response to an epitope in p24 gag (amino acids 263-272, KR WIILGLNK).
Anthony D. Kelleher +38 more
core +1 more source
Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)
Macrophage-enriched peritoneal exudate cells from mice infected with Mycobacterium bovis BCG, macrophage-like tumor cells (PU 5-1.8), and peritoneal macrophages propagated in vitro with macrophage growth factor released tumoricidal activity into the ...
Mannel, D N +5 more
core +1 more source
Cytotoxic Activity of Compounds from
Cancer is a major public health burden in both developed and developing countries. Plant-derived compounds have played an important role in the development of useful anti-cancer agents. The current study was designed to evaluate the cytotoxic activity of
Thao Quyen Cao +5 more
doaj +1 more source

