Results 111 to 120 of about 27,071 (267)

Cytotoxic and genotoxic potential of Achillea millefolium herb methanol and dichloromethane extracts [PDF]

Cancer stands as the leading cause of mortality worldwide, and multidrug resistance represents a significant obstacle in treating the disease, complicating effective treatment strategies. Today, research is shifting towards identifying new natural agents and strategies due to the decreasing effectiveness of available drugs. Plants are promising sources
Ignjatijević, Ana, Cvetković, Stefana, Kukić-Marković, Jelena, Vuletić, Stefana, Ušjak, Ljuboš, Milutinović, Violeta, Ganić, Tea, Mitić-Ćulafić, Dragana, Petrović, Silvana, Nikolić, Biljana   +9 more
openaire  

CYTOTOXICITY ACTIVITY OF PICRIA FEL-TERRAE LOUR. HERBS AGAINST 4T1 AND MCF-7 BREAST CANCER CELLS

Asian Journal of Pharmaceutical and Clinical Research, 2018
 Objective: This study was carried out to investigate the cytotoxic activity toward 4T1 and MCF-7 cell lines of Picria fel-terrae Lour. herb fractions.Methods: P. fel-terrae Lour. herb powder was extracted by maceration method with n-hexane, ethyl acetate, and ethanol solvent. In vitro study was using MTT method toward 4T1 and MCF-7 cell lines.Results:
Urip Harahap, Poppy Anjelisa Zaitun Hasibuan, Panal Sitorus, Denny Satria   +3 more
openaire   +2 more sources

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source

Cancer Cytotoxic and Anti-HIV Potential of Triphala Herb Mixture on from Chae Son, Lampang, Thailand

Journal of Pharmaceutical Research International, 2019
Introduction:  The objective of this study was to compare the stability properties of the two years for the quality of Tri-Pha-La Herbal Drink, Thai traditional and Ayurvedic medicine. This study aimed to compare the anticancer and anti-HIV efficacy of the solvent extracts and gallic acid of the three fruits. The research was done between A.D.
Chanita Naparswad, Jitra Limthongkul, Kanoknetr Suksen, Boonthawan Wingwon, Angkhana Chuajedton, Phansuang Udomputtimekakul, Wipanoot Baison, Punchavee Sombutsiri, Wilart Pompimon   +8 more
openaire   +2 more sources

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Cytotoxic evaluation of different fractions of Salvia chorassanica Bunge on MCF-7 and DU 145 cell lines

Research in Pharmaceutical Sciences, 2016
Because of antimicrobial, antioxidant, and anticancer potential, Salvia chorassanica Bunge (Lamiaceae) has been considered as a popular herb in Iranian traditional medicine.
Alireza Golshan, Elaheh Amini, Seyed Ahmad Emami, Javad Asili, Zahra Jalali, Sarvenaz Sabouri-Rad, Naghmeh Sanjar-Mousavi, Zahra Tayarani-Najaran   +7 more
doaj  

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus. [PDF]

, 2019
Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection.
Jiang, Jiandong, Li, Liang, Li, Xue, Wang, Genzhu, Wang, Xiukun, Xiong, Yan Q, You, Xuefu, Yu, Jie, Zhang, Youwen   +8 more
core  

Evaluation of antileishmanial, antibacterial and brine shrimp cytotoxic potential of crude methanolic extract of Herb Ocimum basilicum (Lamiacea)

Journal of Traditional Chinese Medicine, 2015
To collect and screen for ethnopharmacological properties (antileishmanial, antibacterial and brine lethality assays) of medicinal plan Ocimum basilicum from Peshawar region (34.008 latitude and 71.57 altitudes).In the present study a general antileishmanial activity against Leishmania tropica strair was carried out.
Khan, Imran, Ahmad, Kafeel, Khalil, Ali Talha, Khan, Jangrez, Khan, Yusra Ali, Saqib, Muhammad Shahab, Umar, Muhammad Naveed, Ahmad, Hilal   +7 more
openaire   +2 more sources

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source